Hirudin is extracted from the saliva of leeches and undergoes processes such as separation, purification, sterilization and active preservation.
Its most original state is liquid. The common products in the market are in powder form or capsules.
The hirudin extracted from Japanese leeches has good activity. Experiments have proved that Japanese medical leeches do no harm to the liver and kidneys, are non-toxic and have no side effects, reaching medical standards.
Advantages:
1. Dedicated biotechnology expertise: enzymatic extraction, protein purification and stabilization.
2.Advanced fermentation technology.
3.Protein determination and quantification systems: HPLC, SDS-PAGE or ELISA for hirudin content and purity analysis.
4.Standardized purity and activity testing: for biological activity determination.
5. Contaminant testing: for microbial limits, heavy metals and residual solvents.
6. Stability testing.
7. Rigorous sterilization procedures: including filtration, irradiation or autoclaving (depending on the dosage form).
8. Cold chain logistics: for storage and transportation of active proteins without degradation.
OEM ODM SERVICE
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Process flow chart

What is hirudin used for?
1. Hirudin is mainly used for anticoagulation, which helps maintain blood fluidity and prevent thrombosis. This is because, on the one hand, it has a small molecular weight and good permeability, which can easily dissolve blood clots, and on the other hand, it has no serious side effects.
2. Treat heparin-induced thrombocytopenia (HIT).
3. Natural hirudin has the functions of dredging blood vessels, resisting gout, and improving renal function.
4. Used in medical research.

|
Item |
Specification |
Result |
|
Active |
1000ATU |
Conforms |
|
Extract the source |
Hirudinaria manillensis lesson |
Conforms |
|
Appearance |
Fine Powder |
Conforms |
|
Color |
Brown color |
Conforms |
|
Odor |
Characteristic |
Conforms |
|
Taste |
Characteristic |
Conforms |
|
Partical Size |
100%Through 80 Mesh |
Conforms |
|
Loss on Drying |
≦5.0% |
1.8% |
|
Ash Content |
≦5.0% |
2.5% |
|
Bulk Density |
50-60g/100ml |
Conforms |
|
Solvent Residue |
Eur.Pharm |
Conforms |
|
Pesticide Residue |
Negative |
Negative |
|
Total Heavy Metals |
≤10ppm |
Conforms |
|
Arsenic |
≤2ppm |
Conforms |
|
Lead |
≤2ppm |
Conforms |
|
Total Plate Count |
≤1000cfu/g |
Conforms |
|
Total Yeast & Mold |
≤100cfu/g |
Conforms |
|
E.Coli. |
Negative |
Negative |
|
Salmonelia |
Negative |
Negative |
|
Staphylococcus |
Negative |
Negative |









