L Ergothioneine Powder

1. Product Introduction

L-Ergothioneine (abbreviated as EGT) is a rare, natural and high-efficiency amino acid antioxidant with excellent biocompatibility and biosafety. Widely present in human cells and tissues, EGT cannot be synthesized by the human body and must be obtained from external supplementation. Different from ordinary antioxidants, EGT features ultra-high free radical scavenging activity, long-term cell protection, anti-glycosylation, anti-radiation and anti-inflammatory properties, with stable performance and no cytotoxicity.

We supply high-purity L-Ergothioneine bulk powder and finished capsules, and support customized soft capsule OEM services with years of mature customization experience. Our EGT raw material is tested by HPLC internal standard method with purity up to 99.92% and ultra-high oral bioavailability (up to 96%). Purity is the core factor determining the efficacy of oral EGT supplements, and our high-purity products ensure stable and efficient physiological activity.

2. Core Product Advantages

Ultra-high Purity: Strict HPLC internal standard testing, product purity reaches 99.92%, far exceeding industry standard, ensuring pure and effective ingredients.

High Bioavailability: Excellent human cell affinity, oral bioavailability up to 96%, easy for human body absorption and utilization, realizing efficient nutritional supplementation and cell protection.

Safe & Reliable: Natural non-toxic antioxidant, officially recognized safe ingredient by FDA and EFSA, suitable for long-term human oral and skin external use.

Complete Product Forms: Support bulk powder supply and finished capsule products, and provide one-stop OEM customization of ergothioneine soft capsules.

l -Ergothioneine, also known as EGT. Our company can supply powder and capsules, and has many years of experience in customizing ergothioneine soft capsules for customers.

Production process flow chart :

Both capsules and powder are available.

C-NMR Spectrum 

3. Core Functions & Physiological Efficacy

Domestic and foreign academic studies have fully confirmed that L-Ergothioneine is a multi-functional active ingredient integrating antioxidant, anti-inflammatory, anti-aging, anti-glycosylation and anti-radiation effects. Its comprehensive efficacy is far superior to conventional antioxidants such as vitamin C, with excellent cell protection and physiological regulation capabilities.

Superior Antioxidant Capacity: EGT efficiently scavenges intracellular oxygen free radicals, inhibits oxidative stress damage, and its free radical removal activity is significantly higher than vitamin C and other common antioxidants. It protects cell lipids, proteins and collagen from oxidative damage, delaying cell aging.

Powerful Anti-inflammatory Effect: It significantly inhibits the inflammatory response of muscle cells induced by palmitic acid, relieves lung tissue inflammatory lesions, reduces chronic low-grade inflammation in the body, and improves overall inflammatory state.

Neurological & Cardiovascular Protection: EGT is an essential nutrient for nervous system health, promoting neuronal growth and differentiation. Low serum EGT levels are closely associated with Parkinson's disease and cognitive impairment. It effectively assists in preventing neurodegenerative diseases and improving cardiovascular health.

Professional Skin Repair & Anti-photoaging: As a skin-friendly cosmetic ingredient, EGT resists UV radiation damage, repairs sun-damaged skin cells, enhances cell viability, protects skin collagen, prevents skin lipid peroxidation, and achieves sunscreen, repair and anti-aging effects.

Enhance Immunity & Cell Protection: High cell affinity ensures efficient absorption and utilization by human cells. It supports normal cell growth and cellular immune function, improves body immune response, and resists damage from various cytotoxins.

Anti-glycosylation & Anti-radiation: Effectively inhibit skin and body glycosylation reaction, reduce radiation-induced cell damage, and provide comprehensive body protection for long-term external stimulation.

4. Wide Application Fields

Dietary Supplements: Used in immune regulation, anti-aging, antioxidant and neuroprotective health products, with ultra-high oral bioavailability for efficient nutritional intervention.

Cosmetic & Skin Care Products: Applied in sunscreen, after-sun repair, anti-aging, brightening and anti-glycosylation skin care products.

Functional Food: Used as a safe functional food additive for anti-oxidation and body immunity improvement.

Biomedical Research: Used in research on neurological diseases, cardiovascular diseases and chronic inflammatory diseases.

5. Factory Strength & Quality Control

We own professional plant extraction workshops and OEM aseptic production workshops, equipped with complete advanced production equipment: 6 sets of 6m³ multi-functional extraction equipment, 4 sets of 5m³ reaction kettles, 7 sets of 1500kg/h external circulation evaporation and concentration equipment, 4 sets of 2m³ chromatographic columns, 1 set of 250kg/h spray drying tower, 1 set of 2000kg/h alcohol rectifying tower, and a 400㎡ Class D clean production area.

We implement strict screening and standardized management in raw material procurement and production processing. A complete quality control system covers the whole process from raw material incoming inspection, production monitoring to finished product delivery, ensuring stable high purity, low impurities and consistent batch quality of EGT products.

A large number of studies at home and abroad have confirmed that ergothioneine can not only eliminate oxygen free radicals in cells, but also has excellent effects in sunscreen, anti-aging, anti-radiation and anti-glycosylation. Its antioxidant properties may provide compound therapeutic potential, or may be used as a food additive or cosmetic ingredient.

1. As a natural antioxidant, L Ergothioneine Powder is often used as a ingredient of dietary supplement. Cells in the human body have a good affinity for ergothioneine (EGT). It provides profound protection against oxidative stress, improves inflammatory responses, and improves immune function, making it the best ingredient in supplements to support immune system health. Studies have shown that the theoretical bioavailability of oral ergothioneine supplements may be as high as 96%.
2. Ergothioneine is more effective at scavenging free radicals than typical antioxidants such as vitamin C.
3. It can protect cells from a variety of cytotoxins.
4. EGT is essential for nervous system health and is beneficial for cardiovascular diseases and neurodegenerative diseases. It is a key factor that helps neurons grow and differentiate.
Low serum levels of ergothioneine (EGT) are associated with an increased risk of neurological diseases. Low levels of ergothionein (EGT) have been found in the serum of patients with Parkinson's disease and mild cognitive impairment.
5. Anti-inflammatory. Ergothione can significantly reduce the inflammatory response of muscle cells to the fatty acid palmitic acid. In addition, its anti-inflammatory properties are also reflected in the help of inflammatory diseases of lung tissue.
6. It is one of the friendly ingredients of skin care and has a good repair effect on skin damage caused by ultraviolet radiation. Ergothioneine prevents lipid damage in skin cells and protects collagen in the skin by increasing cell viability.
7. This ingredient can protect cells and support various physiological functions such as normal cell growth and cellular immunity.

1.  As a antioxidant and anti-inflammatory agent, bulk L Ergothioneine is often used as a dietary supplement.

2. Due to its gentle properties on the skin, it is also used as a skin care ingredient.

L Ergothioneine Powder is a natural antioxidant, it is safe and non-toxic. Both the U.S. Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA)  consider synthetic ET supplements to be safe for use in humans in doses of 5 mg per day.

Reference

[1]. Cheah IK, Tang RM, Yew TS, Lim KH, Halliwell B. Administration of pure ergothioneine to healthy human subjects: Uptake, metabolism, and effects on biomarkers of oxidative damage and inflammation. Antioxid Redox Signal. 2017;26(5):193-206.

[2]. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA), Turck D, et al. Statement on the safety of synthetic l-ergothioneine as a novel food - supplementary dietary exposure and safety assessment for infants and young children, pregnant and breastfeeding women. EFSA J 2017;15(11):e05060.

1.We have our own plant extraction workshop and OEM aseptic workshop.

The company has 6 sets of 6m3 modern multi-functional extraction equipment, 4 sets of 5m3 reactors, 7 sets of external circulation evaporation and concentration equipment with an evaporation capacity of 1500kg/h, 4 sets of chromatographic columns with a volume of 2m3, and an evaporation capacity of 250kg/h spray One set of drying tower, one set of rectifying alcohol 2000kg/h rectifying tower, 400㎡ of Class D clean area.

2.We have a sound system and strict and professional standards in raw material selection and procurement, ensuring a complete and comprehensive quality control system from raw material procurement to product delivery.

Double polyethylene bags inside, and high-quality standard carton drum outside.

Shipping by express, air, Sea, and some special line to most Countries.

FAQ

Q1: Can I get free L-Ergothioneine powder samples?

A: Yes, we provide free product samples. Customers only need to bear the corresponding shipping cost.

Q2: What product forms can you supply?

A: We supply 99.92% high-purity EGT powder, finished capsules, and support customized soft capsule OEM processing.

Q3: What supporting test documents can be provided?

A: Complete COA, HPLC purity report and C-NMR spectrum verification reports are available.

Q4: What is your MOQ and delivery time?

A: Standard MOQ is 1kg. In-stock products can be delivered within 3–5 working days after payment confirmation.

Q5: Do you provide bulk discount?

A: Yes, we adopt tiered pricing, and large-quantity purchases can enjoy more favorable wholesale prices.