l -Ergothioneine, also known as EGT. Our company can supply powder and capsules, and has many years of experience in customizing ergothioneine soft capsules for customers.
Advantages
1. The L Ergothioneine we supply has high bioavailability.
2. HPLC test confirmed that the purity of bulk Ergothioneine Powder is ≥99.9%.
Whether oral ergothioneine (EGT) supplements are effective depends on its purity.
Sample real shot:

Production process flow chart :

Both capsules and powder are available.
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C-NMR Spectrum


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Items |
Specifications |
Test Results |
Methods |
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Purity |
≥99.9% |
99.92% |
HPLC(Internal Standard Method) |
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Physical & Chemical Control |
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Appearance |
White crystal |
Conform |
Visual observation |
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Smell |
Characteristic odor |
Conform |
Nose smells |
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pH(50mg/mL,20℃) |
6.0-7.5 |
6.38 |
pH meter |
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Melting Point (Decompose) |
270-271℃ |
270.4℃ |
Melting point detector |
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Optical Rotation |
[a]D≥(+)122°(c= 1,H₂O) |
+124.9° |
Polarimeter (c= 1,H₂O) |
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Crystallite size |
100% pass rate for 50 mesh |
Conform |
Sieve |
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Density |
0.55-0.75g/mL |
0.66 |
Bulk density meter |
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Loss on Drying |
<0.5% |
0.07% |
TGA |
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Total Residual Solvents |
≤200 ppm |
50.06 ppm |
GC |
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Heavy Metals Control: |
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Arsenic |
≤1 ppm |
Conform |
ICP |
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Lead |
≤1 ppm |
Conform |
ICP |
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Mercury |
≤0.2 ppm |
Conform |
ICP |
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Cadmium |
≤0.3 ppm |
Conform |
ICP |
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Total Heavy Metals |
≤10 ppm |
Conform |
ICP |
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Microbiological Control: |
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E.coli |
Negative/25g |
Conform |
USP<62> |
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Staphylococcus aureus Rosenbach |
Negative/25ç |
Conform |
USP<62> |
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Salmonella |
Negative/25g |
Conform |
USP<62> |
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P, aeruginosa |
Negative/25g |
Conform |
USP<62> |
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Total Coliform |
<100 CFU/g |
Conform |
USP<62> |
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Total Yeast and Mold Count |
≤100 CFU/s |
Conform |
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Total Viable Aerobic Count |
≤1000 CFU/ç |
Conform |
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Packing:1kg sterile bag packaging,wrapped in aluminum foil bags |
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Storage:Sealed and stored in cool and dry place,protect from sunlight and moisture |
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What does ergothioneine do for the body?
A large number of studies at home and abroad have confirmed that ergothioneine can not only eliminate oxygen free radicals in cells, but also has excellent effects in sunscreen, anti-aging, anti-radiation and anti-glycosylation. Its antioxidant properties may provide compound therapeutic potential, or may be used as a food additive or cosmetic ingredient.
1. As a natural antioxidant, L Ergothioneine Powder is often used as a ingredient of dietary supplement. Cells in the human body have a good affinity for ergothioneine (EGT). It provides profound protection against oxidative stress, improves inflammatory responses, and improves immune function, making it the best ingredient in supplements to support immune system health. Studies have shown that the theoretical bioavailability of oral ergothioneine supplements may be as high as 96%.
2. Ergothioneine is more effective at scavenging free radicals than typical antioxidants such as vitamin C.
3. It can protect cells from a variety of cytotoxins.
4. EGT is essential for nervous system health and is beneficial for cardiovascular diseases and neurodegenerative diseases. It is a key factor that helps neurons grow and differentiate.
Low serum levels of ergothioneine (EGT) are associated with an increased risk of neurological diseases. Low levels of ergothionein (EGT) have been found in the serum of patients with Parkinson's disease and mild cognitive impairment.
5. Anti-inflammatory. Ergothione can significantly reduce the inflammatory response of muscle cells to the fatty acid palmitic acid. In addition, its anti-inflammatory properties are also reflected in the help of inflammatory diseases of lung tissue.
6. It is one of the friendly ingredients of skin care and has a good repair effect on skin damage caused by ultraviolet radiation. Ergothioneine prevents lipid damage in skin cells and protects collagen in the skin by increasing cell viability.
7. This ingredient can protect cells and support various physiological functions such as normal cell growth and cellular immunity.
Is ergothioneine an anti-inflammatory?
1. As a antioxidant and anti-inflammatory agent, bulk L Ergothioneine is often used as a dietary supplement.
2. Due to its gentle properties on the skin, it is also used as a skin care ingredient.
L Ergothioneine Powder is a natural antioxidant, it is safe and non-toxic. Both the U.S. Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA) consider synthetic ET supplements to be safe for use in humans in doses of 5 mg per day.
Reference
[1]. Cheah IK, Tang RM, Yew TS, Lim KH, Halliwell B. Administration of pure ergothioneine to healthy human subjects: Uptake, metabolism, and effects on biomarkers of oxidative damage and inflammation. Antioxid Redox Signal. 2017;26(5):193-206.
[2]. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA), Turck D, et al. Statement on the safety of synthetic l-ergothioneine as a novel food - supplementary dietary exposure and safety assessment for infants and young children, pregnant and breastfeeding women. EFSA J 2017;15(11):e05060.



1.We have our own plant extraction workshop and OEM aseptic workshop.
The company has 6 sets of 6m3 modern multi-functional extraction equipment, 4 sets of 5m3 reactors, 7 sets of external circulation evaporation and concentration equipment with an evaporation capacity of 1500kg/h, 4 sets of chromatographic columns with a volume of 2m3, and an evaporation capacity of 250kg/h spray One set of drying tower, one set of rectifying alcohol 2000kg/h rectifying tower, 400㎡ of Class D clean area.
2.We have a sound system and strict and professional standards in raw material selection and procurement, ensuring a complete and comprehensive quality control system from raw material procurement to product delivery.


Double polyethylene bags inside, and high-quality standard carton drum outside.
Shipping by express, air, Sea, and some special line to most Countries.



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