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What effect does Carnosic acid have?

Jan 12, 2022

Carnosic acid, a phenolic diterpenoid lipid-soluble compound with molecular formula C20H2804. The relative molecular mass was 332.43, which appears as a yellow-green powder and is very soluble in chloroform and acetone, it is the most antioxidant active component of rosemary, in a research analysis on rosemary leaves, we found that all phenolic diterpenoids including rosmarinol and carnosol were formed as a result of oxidation of carnosic acid.CA has been widely used in food additives, actinification, feed, medical and health products because of its safety, high efficiency and heat resistance.

Carnosic acid acts as an important natural antioxidant and the mechanism of antioxidant action is by itself as a chain-breaking radical terminator, which effectively inhibits the peroxidation chain reaction by trapping peroxyl radicals. According to the lipid solubility characteristics of CA, which can be used in oily foods, it effectively inhibits the oxidation and rancidity of oils and fats.

Modern studies have shown that carnosic acid can effectively inhibit cancer cell proliferation and has the potential to be developed into a specific new agent for the treatment of hematological malignancies, it has the efficacy of weight loss to control body weight by modulating the body's absorption capacity for fat, CA prevents lipid accumulation in hepatocytes, treats the fatty liver, corrects stop metabolic acidosis, reduces the absorption of nonheme iron, prevents damage to protein structure, treats insulin resistance, In addition, CA also has better anti-inflammatory and antimicrobial activities.

Carnosic acid

With the increase of living standards and increasing concern about health, rosemary, as a natural green plant, has become a research hotspot because of its safety and nontoxicity, while having better antioxidant and preservative properties. In recent years, there have been a lot of reports and patents on rosemary plants from inside to outside, which can be widely used in the fields of pharmaceutical health products, acidification, food additives, and so on, and has a promising development prospect.



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