What food is highest in fisetin?
Fisetin is a flavonoid and antioxidant found in fruits and vegetables, including strawberries, apples and cucumbers.
Fisetin is particularly abundant in strawberries, which are also found in apples, persimmons, onions, and cucumbers, but in much smaller amounts. Strawberries are the richest dietary food source of fisetin.
Fisetin can be used as a pharmaceutical ingredient, oral dietary supplement, and medical food.
What are the benefits of taking fisetin?
A study in Frontiers in Chemistry shows that flavonoids show "anti-inflammatory and anti-aging potential."
1. Among the 13 flavonoids tested, fisetin is the most effective inhibitor of hexosaminidase secretion, which can inhibit the production of inflammatory cytokines.
2. A paper published in the journal EBioMedicine in 2018 by researchers from the University of Minnesota Medical School and Mayo Clinic showed that not only can drugs help extend the lifespan of old mice, but Fisetin, which is found in fruits and vegetables, can also maintain the health of the body and extend the lifespan of mice.
3. Fisetin can prevent urticaria-like symptoms and inhibit mast cell activation by binding to MRGPRX2 to inhibit calcium flow and degranulation of cytokines and chemokines, suggesting that fisetin may be a new drug for the treatment of chronic urticaria.
4. Currently, clinical trials of fisetin have been applied to coronavirus, osteoarthritis, etc.
5. Reduce chronic inflammation
Chronic inflammation contributes to most chronic diseases. In preclinical trials, fisetin blocked the activation of nuclear factor-kappa B (NF-kB), a master regulator of inflammation. This action prevented the release of pro-inflammatory compounds. Fisetin prevented learning and memory decline and also reduced levels of inflammatory compounds that are elevated in Alzheimer's disease and other neurodegenerative diseases.
6. The latest scientific research has found that fisetin may have a potential protective role in slowing placental aging and improving heart function during pregnancy.
7. Promotes Heart Health
Fisetin may help promote cardiovascular health in a number of ways.
The analysis reports that the antioxidant may induce heart cell regeneration by activating genes involved in cell proliferation. It may protect against ischemic damage after a heart attack. There is some evidence that fisetin may also help prevent strokes.
