Tetrahydrocurcumin Powder

1. Product Introduction

Tetrahydrocurcumin (THC) is a high-activity hydrogenated derivative purified and hydrogenated from natural turmeric rhizome curcumin. It is the core active metabolite of curcumin in the human body. Compared with conventional curcumin, tetrahydrocurcumin undergoes structural optimization, featuring higher stability, superior antioxidant capacity and significantly improved bioavailability, making it an upgraded and high-value version of curcumin active ingredients.

Tetrahydrocurcumin powder, or THC for short, is hydrogenated from curcumin isolated from turmeric rhizomes and is the main metabolite in the body. Compared with curcumin, tetra hydro curcumin has higher stability, stronger antioxidant properties, and better bioavailability than curcumin.

Available in powder and Tetrahydrocurcumin Capsule form.We have our own factory and can provide customized services based on customer requirements, including OEM and ODM.We can create tablets, capsules, and powder.

turmeric extract, tetrahydrocurcuminoids, turmeric supplement, turmeric tablets, curcumin powder, curcuminoids, curcumin tablets, curcumin supplement, turmeric and black pepper capsules, turmeric and ginger supplement are available.

Curcumin is metabolized in the body into glucuronic acid conjugates, sulfate conjugates, dihydrocurcumin, tetrahydrocurcumin and hexahydrocurcumin, and dihydro and hexahydro are converted into tetrahydrocurcumin. Therefore, tetrahydrocurcumin has become a research hotspot at home and abroad in recent years.

1. Anti-oxidize effect
The molecular structure of tetrahydrocurcumin powder contains phenolic hydroxyl and β-diketone structures and is a natural antioxidant.
On the one hand, it can scavenge the generated free radicals, and on the other hand, it can also inhibit the generation of free radicals, thereby breaking the chain reaction of free radicals and blocking their damage to the skin and body. Its ability to inhibit DPPH free radicals is far superior to vitamin C, glabridin, and kojic acid.

The reducing ability of tetrahydrocurcumin to Fe3+ increases as the concentration increases. When the concentration reaches 10 μmol/L, the reducing ability of tetrahydrocurcumin to Fe3+ is greater than that of vitamin C at the same concentration.

2. Inhibit melanin production

Tetrahydrocurcumin not only protects cells from ultraviolet damage, but also plays a very good role in inhibiting tyrosinase activity. Its inhibitory effect on tyrosinase is more than 18 times that of arbutin.

3. Anti-inflammatory
The anti-inflammatory effect of tetrahydrocurcumin is by inhibiting the main inflammatory mediator cyclooxygenase, etc., thereby effectively reducing skin inflammation and reducing the formation of erythema.

4. Core Efficacy & Mechanism

4.1 Powerful Antioxidant Capacity

Tetrahydrocurcumin contains unique phenolic hydroxyl and β-diketone structures, serving as a high-efficiency natural antioxidant. It achieves dual antioxidant effects: scavenging existing free radicals in the body and inhibiting new free radical generation, cutting off free radical chain reactions and reducing oxidative damage to skin and human tissues.

Its DPPH free radical scavenging ability is far superior to Vitamin C, Glabridin and Kojic Acid. In terms of Fe³+ reduction ability, tetrahydrocurcumin at a concentration of 10μmol/L shows stronger reducing activity than Vitamin C at the same concentration, with top-level antioxidant performance among natural skincare ingredients.

4.2 Efficient Melanin Inhibition & Whitening

THC effectively protects skin cells from UV-induced oxidative damage and strongly inhibits tyrosinase activity-the core enzyme of melanin synthesis. Its tyrosinase inhibitory effect is 18 times higher than Arbutin. It fundamentally blocks melanin production, fades pigmentation, brightens dull skin, and is suitable for various high-end whitening and brightening formula combinations.

4.3 Excellent Anti-Inflammatory & Soothing Effect

Tetrahydrocurcumin inhibits the expression of core inflammatory mediators such as cyclooxygenase, effectively relieving skin inflammatory reactions, reducing UV erythema and redness, soothing sensitive and irritated skin, and repairing damaged skin barriers.

5. Wide Application Fields

High-End Skincare Products: Widely used in whitening essence, brightening lotion, soothing repair cream, anti-oxidation facial mask and other formulas. It can be compounded with other whitening ingredients to achieve synergistic brightening effects.

Healthcare & Biomedical Field: Tetrahydrocurcumin solid dispersion has been verified by in vivo experiments to have potential antidepressant activity, which can be applied to the research and development of antidepressant health products, functional foods and food additives.

6. Product & Factory Advantages

Ultra-High Purity: The product purity reaches 98.63%, with low moisture, low ignition residue and ultra-safe heavy metal and microbial indicators, fully compliant with cosmetic and food-grade standards.

Stable & High Activity: Optimized hydrogenated structure solves curcumin's light-sensitive and easy-decomposition problems, with stable activity and no pigment precipitation, suitable for high-end transparent and whitening formulas.

Diversified Product Forms: In stock with powder, capsule, tablet and other forms, supporting arbitrary formula compounding.

Powerful Customization Capacity: Independent factory supports one-stop OEM/ODM services including raw material customization, finished product processing, private label packaging and formula development.

7. OEM & Custom Service

We provide full-link customized solutions for tetrahydrocurcumin products: support high-purity powder customization, capsule/tablet finished product processing, compound formula development, and private label packaging customization. Cover cosmetic raw materials, functional health products and food additive production, meeting personalized customization needs of global customers.

8. Packaging & Storage

Packaging: 1kg aluminum foil bag, 25kg standard export drum. Customized packaging is available.

Storage Condition: Sealed and stored in a cool, dry and dark environment, avoid high temperature and strong light to maintain stable product activity and purity.

FAQ

Q1: What is the difference between tetrahydrocurcumin and ordinary curcumin?

A: Tetrahydrocurcumin is the upgraded metabolite of curcumin. It has higher stability, no yellow staining, better solubility, higher bioavailability, and far stronger antioxidant and whitening efficacy than curcumin.

Q2: What are the core skincare effects of THC?

A: It mainly includes high-efficiency antioxidant free radical removal, 18 times arbutin-level tyrosinase inhibition and whitening, and anti-inflammatory soothing repair, being an all-round natural skincare raw material.

Q3: Is tetrahydrocurcumin easy to oxidize and deteriorate?

A: No. Its molecular structure removes unstable conjugated double bonds, with excellent light and thermal stability, not easy to oxidize and deactivate, and has a longer formula shelf life.

Q4: What products can tetrahydrocurcumin be added to?

A: It is widely used in whitening skincare products, antioxidant essences, soothing repair products, as well as functional health foods and antidepressant-related health product formulations.

Reference

[1]. Novaes J.T., Lillico R., Sayre C.L., Nagabushnam K., Majeed M., Chen Y., Ho E.A., Oliveira A.L.P., Martinez S.E., Alrushaid S., et al. Disposition, Metabolism and Histone Deacetylase and Acetyltransferase Inhibition Activity of Tetrahydrocurcumin and Other Curcuminoids. Pharmaceutics. 2017;9:45. doi: 10.3390/pharmaceutics9040045.

[2]. Wu J.C., Tsai M.L., Lai C.S., Wang Y.J., Ho C.T., Pan M.H. Chemopreventative effects of tetrahydrocurcumin on human diseases. Food Funct. 2014;5:12–17.