1. Product Introduction
Bimatoprost is a synthetic prostaglandin F2α analog, commercially sold under the brand name Lumigan in the United States, Canada, and European markets. It is a high-purity pharmaceutical-grade active ingredient with two core clinical effects: effectively reducing intraocular pressure and promoting hair follicle growth. With stable chemical properties and ultra-high purity, it is widely used in pharmaceutical raw materials and professional eyelash growth functional formulations.
Chromatogram:


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TESTS |
SPECIFICATIONS |
RESULTS |
|
|
Purity |
NLT99.0% |
99.89% |
|
|
Descriptior |
White powder |
White powder |
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|
Identification(by HPLC) |
RT of the sample should match with standard in the Related substances |
Complies |
|
|
Solubility |
Very soluble in ethanol,methanol slightly soluble in water |
Complies |
|
|
Water |
NMT 1.0% |
0.60% |
|
|
Specific rotation[a]20 (C=2,CH₃OH) |
Between +33° to +39° |
+37.1° |
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|
Residue on ignitior |
NMT 0.1% |
0.04% |
|
|
Heavy metals |
NMT 10ppm |
Complies |
|
| Residual solvent | |||
|
Isopropanol Ethyl acetate Methyl tert-butyl ether N.N-Dimethylformamide |
NMT 0.5% NMT 0.5% NMT 0.5% NMT 0.088% |
Not Not Not Not |
detected detectec detected detected |
|
Related Substances(by HPLC 15β-bimatopros 15-Keto derivative 5,6-trans isomer Other single max impurity Total other impurities |
NMT0.2% NMT0.2% NMT0.2% NMT0.1% NMT0.5% |
0.02% 0.01% 0.08% Not detected Not detected |
|
Does bimatoprost grow hair?
1. It is mainly used to treat glaucoma and high intraocular pressure symptoms. It reduces intraocular pressure by increasing the outflow of aqueous fluid from the eye.
2. Clinically, it was found that some patients who used bimatoprost would have eyelash growth, increase, and growth. After that, bimatoprost was used in clinical trials for eyelash beauty and was approved by the US FDA in December 2008 as an ingredient to promote eyelash growth. However, it needs to be used under professional guidance and in accordance with the requirements of the product instructions.
3. In vitro culture of human hair follicle cells, three groups of controlled control trials found that after using bimatoprost, the in vitro cultured hair would be healthier, grow faster and longer, which seems to prove that bimatoprost can make hair grow faster and longer. However, this experiment was an in vitro culture and short-term culture experiment.
2. Core Functions & Mechanism
2.1 Medical Effect: Reduce Intraocular Pressure
Bimatoprost is a classic clinical ophthalmic active ingredient, mainly used for the treatment of glaucoma and ocular hypertension. It effectively reduces intraocular pressure by promoting the outflow of aqueous humor in the eye, relieving eye pressure symptoms and protecting ocular health.
2.2 Cosmetic Effect: Eyelash Growth Promotion
The eyelash growth effect of bimatoprost was accidentally discovered in clinical ophthalmic treatment: patients using bimatoprost eye drops showed phenomena of thicker, denser and longer eyelashes. Subsequently, it underwent professional cosmetic clinical trials and was officially FDA-approved in December 2008 as an effective active ingredient for eyelash growth.
In vitro human hair follicle cell controlled experiments further verified that bimatoprost can activate hair follicle vitality, accelerate hair growth rate, prolong hair growth cycle, and make hair thicker, healthier and longer. It is the core raw material of high-efficiency professional eyelash growth serum.
3. Important Safety Instructions
Although bimatoprost has a significant eyelash growth effect, it belongs to pharmaceutical-grade synthetic prostaglandin ingredients with strict application limitations:
1. Pregnancy Safety Level: FDA pregnancy rating is Class C, which may have potential adverse effects on the fetus, and is prohibited for pregnant women.
2. Professional Use Required: It is a prescription-derived active ingredient, which must be used in strict accordance with product specifications and professional guidance, and is not suitable for casual civilian use.
3. Risk Warning: The cosmetic application safety of bimatoprost still needs further systematic evaluation, with certain application threshold and safety risks.
4. Product Advantages
Ultra-High Purity: The product purity reaches 99.89%, far higher than the 99.0% industry standard, with extremely low impurity content and stable batch quality.
Zero Residual Solvent: All residual solvents are not detected, meeting pharmaceutical-grade safety standards.
Low Impurity Index: All related substances and single impurities are far below the limit standard, with excellent stability and high safety.
Dual Functional Value: It has both clinical intraocular pressure reduction and professional eyelash growth promotion effects, with high application value in pharmaceutical and high-end cosmetic fields.
5. Main Application Fields
Pharmaceutical Field: Raw material for glaucoma and ocular hypertension treatment preparations.
High-End Cosmetics: Professional medical-grade eyelash growth serum raw materials for thickening, densifying and lengthening eyelashes.
Scientific Research: In vitro hair follicle research and prostaglandin pharmacological research.
FAQ
Q1: How does bimatoprost promote eyelash growth?
A: It activates human hair follicle cell vitality, accelerates hair growth metabolism, prolongs the hair growth cycle, and effectively improves eyelash density, length and thickness.
Q2: Is bimatoprost safe for cosmetic use?
A: It is FDA-approved for eyelash growth use, but belongs to pharmaceutical-grade ingredients with Class C pregnancy risk. It needs to be used in strict accordance with specifications and professional guidance, with certain application thresholds.
Q3: What is the purity of your bimatoprost powder?
A: Our product purity is up to 99.89%, with undetected residual solvents, ultra-low heavy metals and impurities, reaching premium pharmaceutical-grade standards.
Q4: What are the core applications of bimatoprost?
A: It is mainly used for clinical treatment of glaucoma and ocular hypertension, as well as the production of professional medical-grade eyelash growth products.






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