Sodium Deoxycholate

Sodium Deoxycholate

Details
CP2015,USP34
Appearance: White Crystal powder
Specification: 99%
CAS: 302-95-4
Chemical Formula: C24H41NaO4
Molecular Weight: 416.58
Test Method: HPLC
MOQ:0.1- 1KG
OEM ODM Available
Category
Active Pharmaceutical Ingredients
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Description
Technical Parameters

Deoxycholic acid is one of the most important bile acids in the human body. Sodium deoxycholate is the sodium salt of deoxycholic acid, a bile acid compound that exists naturally in the human body. In the intestine, it can emulsify and promote the decomposition of fat in food. It appears as a white crystalline powder.USP standard and CP standard or others are available.

Sodium deoxycholate

USP34

Testing Method

USP34

Items Tested

Specification

Result

Characters

White, crystalline powder

White crystalline powder

Identification

A.B.C: positive reactions

Conforms

Assay

99.0% ~ 101.0%

99.70%

Melting Point

153~158℃

155.0 ~ 156.0℃

Acidity

Meet the specifications

Conforms

Chromatographic purity

Secondary spots ≤ 0.5%

Sum ≤ 1.0%

Conforms

Loss on Drying

≤ 1.0%

0.18%

Residual on Ignition

≤ 0.15%

Conform

Heavy Metal

≤20 ppm

Conforms

CP2015

Testing Item 

Specifications

Results

Ref standard CP2015  

Description 

White powder, no odor and smell 

White powder

Content (The uv method to detect)

≥ 97%

98.2%

Solubility (Solvent with water and alcohol)

Clear and no deposit 

Complies 

Arsenic salt

≤0.0002%

Complies 

Than the curl

+ 40°~+ 45°

+ 43.5°

Sodium 

5.0%~6.1%

5.2%

Loss on Drying 

5.0%

1.63%

Heavy Metal 

≤20ppm

Complies 

Note: This product was tested as CP2015 Standard and the results are ok.

Sodium deoxycholate

1. Sodium deoxycholate can dissolve cell membranes and kill fat and muscle cells.
2. And the single ingredient sodium deoxycholate is no different from the compound preparation in these aspects.
It can effectively lyse cells and viruses and destroy the interaction between proteins.

What is Sodium Deoxycholate used for?

1. It can be used to lyse cells and dissolve proteins that are difficult to dissolve in water.
2. It can be used in biomedical research and bile lysis experiments.

It is also one of the main ingredients of intravenous preparations.
3. As a surfactant, sodium deoxycholate is an important anionic surfactant.
4. Absorption promoter. It can be used as a transdermal absorption promoter because of its good stability and absorption promoting function. It not only acts as a stabilizer for the main drug to enhance the antioxidant effect, but also has the function of promoting the absorption of the main drug through the skin, and has no side effects on biofilm or skin. In short, this substance can fully improve the bioavailability of drugs and can be biodegraded by the body.

5. As detergents. Sodium deoxycholate and sodium cholate are bile salt detergents, both of which are anionic detergents.
These detergents work by disrupting cell membranes and membrane proteins.

Sodium deoxycholate

Sodium deoxycholate

Sodium deoxycholate

Sodium deoxycholate

Sodium deoxycholate

Sodium deoxycholate

 

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