4,4'-Dimethoxychalcone

1. Product Introduction

4,4'-Dimethoxychalcone (CAS 2373-89-9) is a biologically active natural phenolic compound belonging to the chalcone family. It serves as a key biosynthetic precursor for flavonoids and isoflavonoids with extensive research value in pharmaceutical and biomedical fields. This compound can be artificially synthesized via mature laboratory processes and exhibits multiple pharmacological activities, including anti-inflammatory, antioxidant, antimicrobial, anti-diabetic and anti-tumor effects. It has great development potential for the adjuvant treatment of inflammatory disorders, microbial infections and various chronic diseases.

2. Molecular Structural Characteristics

4,4'-Dimethoxychalcone features a classic chalcone skeleton structure. Its molecular formula is C₁₇H₁₆O₃. The molecular structure consists of two aromatic benzene rings connected by a three-carbon α,β-unsaturated carbonyl system - the typical structural feature of chalcones. Methoxy groups (-OCH₃) are symmetrically attached to the 4-position of the two aromatic rings, forming its stable and highly active molecular configuration.

Its structure:

Dimethoxychalcone is a chalcone backbone with methoxy groups (-OCH₃) connected to the fourth position of each aromatic ring.
The molecular formula is C17H16O3.
The structure consists of two aromatic rings joined by a three-carbon α,β-unsaturated carbonyl system (a characteristic of chalcones).

3. Core Pharmacological Activities & Efficacy

Powerful Antioxidant Activity: 4,4'-Dimethoxychalcone acts as an efficient free radical scavenger, effectively eliminating excess free radicals in the body, reducing oxidative stress damage, and protecting cells from oxidative aging and lesions.

Significant Anti-inflammatory Effect: It can significantly inhibit the secretion and expression of pro-inflammatory mediators, block inflammatory response pathways, and relieve acute and chronic inflammatory reactions, showing good application potential for inflammatory-related disease intervention.

Broad-spectrum Antimicrobial Property: Possesses effective antibacterial and antifungal activities, capable of inhibiting the growth and reproduction of harmful microorganisms, and can be used as a key raw material for the research and development of new anti-infection preparations.

Potential Antidiabetic Effect: Relevant studies have verified that it can regulate body glucose metabolism, assist in balancing blood sugar levels, and has potential development value for diabetes and metabolic syndrome intervention.

Anti-cancer & Anti-tumor Potential: It has selective cytotoxicity against a variety of tumor cell lines, which can effectively inhibit cancer cell proliferation and induce tumor cell apoptosis, providing a new research direction for anti-tumor drug development.

4. Main Application Fields

Pharmaceutical & Biomedical Research: Serves as a core research raw material for the development of new anti-inflammatory, antimicrobial, hypoglycemic and anti-tumor innovative drugs.

Biological Research Reagents: Widely used in cell pharmacology, molecular biology and metabolic mechanism research as a standard active chalcone reagent.

H-NMR： 

Liquid chromatography-mass spectrometry： 

1. Antioxidant:

4,4′-dimethoxychalcone may act as a free radical scavenger, reducing oxidative stress.
2. Anti-inflammatory:

It has been shown to inhibit the production of pro-inflammatory mediators, useful in treating inflammation.

3. Antimicrobial:

It may have antibacterial and antifungal properties, making it a candidate for treating infections.
4. Antidiabetic:

Studies suggest potential benefits in regulating blood sugar levels.
5. Anti-cancer:

Studies suggest that it may have cytotoxic effects on certain cancer cell lines, possibly inducing apoptosis and inhibiting cell proliferation.

Used in Pharmaceutical and medical research.

It can be used as an ingredient for developing new therapeutic drugs.

FAQ

Q1: Can I get free 4,4'-Dimethoxychalcone powder samples?

A: Yes, we provide free product samples. Customers only need to bear the corresponding shipping cost.

Q2: What supporting test documents can you provide?

A: We provide complete COA, HPLC purity report, H-NMR and LC-MS spectrum data to support customer testing and research.

Q3: What is your MOQ?

A: The standard MOQ is 1kg. Small trial orders are acceptable for laboratory research use.

Q4: What is your delivery cycle?

A: In-stock products can be delivered within 3–5 working days after payment confirmation.

Q5: Do you offer bulk discount?

A: Yes, we provide tiered pricing, and larger purchase quantities enjoy more favorable wholesale prices.