What Is The Difference Between Softgel And Capsule?

Capsules can be divided into hard capsules and soft capsules. According to different release characteristics, they can be divided into sustained-release capsules, controlled-release capsules, enteric-coated capsules, etc.
Advantages of hard capsules:
Suitable for filling solid drugs such as powders or granules.
The manufacturing process is relatively simple and the cost is low.
The dosage can be easily adjusted to provide patients with personalized treatment options.
In some cases, hard capsules can be opened to allow the drug to be sprinkled directly on food for administration.
Disadvantages of hard capsules:
Not suitable for filling liquids or semi-solids, as this may cause the capsule shell to soften or break.
For some patients, it may be more difficult to swallow than soft capsules.

Advantages of soft capsules:
Can be filled with liquids, gels or oily substances, especially suitable for products containing oil-soluble nutritional supplements or drugs.
Provide good bioavailability, making the drug more easily absorbed by the body.
Can mask the bad taste and improve patient compliance with medication.
The capsule shape is smooth and easy to swallow.
Disadvantages of soft capsules:
The manufacturing process is relatively complicated, requiring special equipment and technology, and the cost is high.
There are high requirements for storage conditions, and high temperature and humidity need to be avoided, otherwise the capsule shell may soften or stick.
Due to its closed nature, the drug dosage cannot be adjusted.

Most of the filling materials of soft capsules are liquid substances, such as oily drugs, drug solutions, suspensions or emulsions.
A. Pure oil solution: base oil + API + antioxidant + others
B. Oily suspension: base oil + API + antioxidant + suspending agent + others
C. Aqueous suspension: aqueous base + API + antioxidant + suspending agent + others