Scientists conduct observational studies on large-scale epidemiology. They found that supplementing with taurine, spermidine, and ergothioneine promotes longevity.
1. In the large epidemiological study EPIC-Norfolk, which lasted over 25 years, researchers found there is a correlation between taurine levels in the blood and the risk of age-related diseases. Oral taurine has been shown to improve aging in randomized controlled studies in humans.
What is spermidine ?
2. Spermidine powder can also achieve anti-aging effects by supporting autophagy, which is the phagocytosis of old or damaged cells.
Spermidine levels decrease with age. Observational human epidemiological studies have shown that higher spermidine intake is associated with lower risk of chronic disease and lower mortality.
Ergothioneine health benefits
3. Dr. B. D. Paul of Hopkins University School of Medicine in the United States discovered in experiments related to ergothioneine that ergothioneine powder is a long-lasting natural antioxidant that enters the mitochondria and nucleus. It protects mitochondria from oxidative damage and directly removes reactive oxygen species. Free radicals remove aging factors from the root.
According to the Proceedings of the National Academy of Sciences, Bruce Ames, a professor in the Department of Biochemistry and Molecular Biology at the University of California, calls ergothioneine a "longevity nutrient."
Reference
[1]. Baliou S, Adamaki M, Ioannou P, et al. Protective role of taurine against oxidative stress (Review). Mol Med Rep. 2021 Aug;24(2).
Schroeder S, Hofer SJ, Zimmermann A, et al. Dietary spermidine improves cognitive function. Cell Rep. 2021 Apr 13;35(2):108985.
[2]. Paul, B.D.; Snyder, S.H. The unusual amino acid L-ergothioneine is a physiologic cytoprotectant[J]. Cell Death Differ. 2010, 17, 1134–1140.
