In a study published this year in Nutrients, researchers searched data from thousands of human intervention studies on a variety of ingredients and finally found that the following ingredients have a significant effect on human blood sugar control. .
1. Curcumin
A comprehensive analysis of 7 studies showed that curcumin can significantly reduce fasting blood glucose levels in patients with type 2 diabetes, by approximately 12 mg/dL (≈0.67 mmol/L). The effective curcumin doses in these studies ranged from 300mg to 600mg per day. Curcumin can inhibit gluconeogenesis and reduce hepatic lipid metabolism by activating glycolysis, and can also promote pancreatic β-cell function by enhancing anti-inflammatory and antioxidant properties, thereby enhancing insulin sensitivity.
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2. Crocin
There is a special carotenoid component in saffron - crocin.
The combined results of 11 studies found that saffron supplementation reduced fasting blood glucose by 7.06 mg/dL (≈0.39 mmol/L) in patients with type 2 diabetes or metabolic syndrome, with daily supplementation of 1.5-3 g. According to the Chinese Pharmacopoeia, the daily dose of saffron for adults is 1-3 grams.
3.Black cumin extract
Black cumin intake can significantly reduce fasting blood sugar levels in patients with type 2 diabetes, with a reduction of up to 26.33 mg/dL (≈1.46 mmol/L). The most common dosage is black cumin powder, 0.5 g-3 g per day, and black cumin natural oil, 2.5-5 mL a day.
Black cumin seeds contain active ingredients such as thymoquinone, musquinone and thymol. Studies have shown that their active ingredients can reduce oxidative stress and maintain the integrity of pancreatic beta cells. Thymoquinone has been shown to reduce hepatic glucose production, serum glucose levels, and insulin levels.
Black cumin seed oil is the extracted form of black cumin seed, which concentrates its active ingredients and exists in the form of health care products. Dosage is 2.5-5 mL per day.
Reference
[1].Garza, M.C.et al. Effect of Aromatic Herbs and Spices Present in the Mediterranean Diet on the Glycemic Profile in Type 2 Diabetes Subjects: A Systematic Review and Meta-Analysis. Nutrients 2024, 16, 756.
