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Physiological function of glutathione

Aug 27, 2021

Too many free radicals produced by the body's metabolism can damage biofilms, invade life molecules, accelerate aging, and induce tumors or atherosclerosis. Glutathione plays an important role in the biochemical defense system , there is many physiological functions.

Its main physiological function is to remove free radicals from the body as an important antioxidant, protecting many molecules such as proteins and enzymes.The structure of GSH contains a lively carbohydrate-SH, which is easily oxidized and dehydrogenated, a specific structure that makes it the main free radical scavenger in the body.

For example, when a small amount of H2O2 is produced in cells, GSH, under the action of glutathione peroxidase, reduces H2O2 to H2O, which itself is oxidized to GSSG, which is reduced by reductase present in the liver and red blood cells, and receives H to GSH, so that the removal of free radicals in the body can be sustained.

Physiological function of glutathione

It not only eliminates human free radicals, but also improves the body's immunity. it maintains health, anti-aging, which can also protect hemoglobin from hydrogen peroxide, free radicals and other oxidation so that it continues to function normally the ability to transport oxygen. Some hemoglobin in red blood cells in the hydrogen peroxide and other oxidants, in which the trivalent iron oxidation, so that hemoglobin into high iron hemoglobin, thus losing the ability to carry oxygen.

It also produces water and oxidizing glutathione by binding directly to oxidants such as hydrogen peroxide, and restores high iron hemoglobin to hemoglobin. There is a lot content in red blood cells, which is important to protect the urethane of proteins in a reduced state, to prevent hemolysis.


Glutathione protects the enzyme molecule -SH-based, it is conducive to the play of enzyme activity, it can restore the activity of the destroyed enzyme molecule - SH-based function, so that the enzyme regains activity. it can also inhibit ethanol from harming fatty livers produced by the liver.

With a strong protective effect on symptoms such as radiation and white blood cell reduction for radioactive drugs. it can be combined with toxic compounds, heavy metal ions or carcinogens entering the body, and promote their excretion that play a role in neutral and detoxifying.

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