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Is the effect of different Panax Notoginseng Saponins extraction the same?

Nov 17, 2020

Ginseng is the dry root of the Araliaceae plant ginseng (Panax ginseng CA Mey). It is a perennial herb and prefers a cool, humid climate.;

Ginseng is known as the "King of Herbs" and one of the famous "Three Treasures of Northeast China". Panax Notoginseng Saponins.jpg

It has always been a precious medicinal material of Chinese medicine in my country. Sweet, slightly bitter, and lukewarm, it can promote body fluids ,soothe the nerves, and enhance immunity. The main active ingredient is Panax Notoginseng Saponins. So far, more than 30 species have been isolated, among which are ginsenosides Ra1, Ra2, Ra3, Rb1, Rb2, Rb3, Rc, Rd, Re, Rf, Rgl, Rg2, Rg3, Rhl, etc.

There are many extraction methods for ginsenosides, such as immersion method, reflux extraction method, ultrasonic extraction method, alcohol-adsorption resin method and microwave method.

Traditional extraction of Panax Notoginseng Saponins mostly uses traditional heating and reflux extraction methods, but there are many disadvantages. In recent years, the wet pulverization extraction method and the ultrasonic extraction method have been applied to the extraction of chemical components of traditional Chinese medicine. Among them, the ultrasonic extraction time is short and the yield is high. The wet pulverization extraction method is used for the extraction of the effective ingredients of traditional Chinese medicine. The extraction rate of the effective ingredients is significantly increased, the extraction rate is high, and the extraction time is significantly shortened. Using reflux extraction method, ultrasonic water extraction method, wet method, and wet crushing extraction method will affect the extraction rate of ginsenoside Re and Rb1. The extraction rates of ginsenosides in each group are significantly different. The extraction rates of ginsenosides Re by reflux extraction method, ultrasonic water extraction method, wet method, and wet crushing method are 83.38% and 90%, respectively. 23%, 96.78%; The extraction rates of ginsenoside Rb1 were 73.34%, 80.11%, and 90.71%, respectively. The time used by the three extraction methods is quite different. The extraction time of reflux is 4h, the time of ultrasonic extraction is 120min, and the extraction method of wet crushing is 40min.

In terms of extraction time and energy consumption, the latter two methods are simple and quick to operate. They have a higher extraction rate than traditional reflux extraction methods, which can replace reflux extraction, they are widely used in industrial production.

Through the comparison of several processes and the final comprehensive analysis, it is shown that the wet pulverization extraction method has the best effect, the ultrasonic water extraction method is second, and the reflux extraction method has the worst effect.


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