Does potassium azeloyl diglycinate help with acne?

Apr 02, 2024

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What is potassium azeloyl diglycinate made of ?

 

Potassium azeloyl diglycinate is a compound composed of azelaic acid and the amino acid glycine. Azeloyl diglycinate potassium salt is a water-soluble compound that is commonly used in cosmetics.

PAD is gentle and non-irritating, it is suitable for sensitive skin.

 

Does potassium azeloyl diglycinate help with acne?

 

Potassium Azeloyl Diglycinate, found in many acne products and formulas, is a derivative of the famous acne-fighting ingredient azelaic acid. Azelaic acid in the skin is an inflammatory signaling compound. Azelaic acid has been used for 50 years. Azelaic acid exists in the secretions of some plants and microorganisms in nature, but the content is very low. Currently, the main production method is chemical synthesis.

Potassium Azeloyl Diglycinate is a safe, highly effective, and multifunctional cosmetic ingredient.
As the potassium salt of diamine, its appearance solves many of the difficult formulation problems of azelaic acid.

 

The formula is the carrier of the active ingredient, and the formula enhances the effectiveness of the active ingredient. The meaning of compatibility is
Several raw materials are combined to produce the best results, including synergy.

Some active ingredients are inherently unstable and require formulation to ensure their long-term stability to ensure efficacy. The availability of some active ingredients is not good, and formulations are needed to ensure the cosmetic effects of some active ingredients.

A good formulation should follow the following principles:
The components in the formula have good compatibility, do not react chemically with each other, and have synergistic effects.

 

Potassium azeloyl diglycinate with salicylic acid


Potassium azeloyl diglycinate + salicylic acid, this formula is designed for oily, acne-prone skin.
Potassium azeloyl diglycinate has anti-inflammatory and antibacterial properties, which helps regulate oil production and reduce pigmentation.

Salicylic acid is a pore-unclogging beta-hydroxy acid (BHA) that penetrates deep into pores to dissolve blackheads and oil to prevent breakouts. Salicylic acid also has anti-inflammatory properties, reducing redness and swelling caused by acne.

Azelaic acid

Potassium azeloyl diglycinate with vitamin c


On the one hand, vitamin C (ascorbic acid) is known for its powerful antioxidant properties, preventing free radical damage by protecting the skin from UV radiation and pollution. On the other hand, it plays a key role in collagen synthesis, promoting skin elasticity and firmness.
In addition, vitamin C, like Potassium azeloyl diglycinate, can improve uneven skin tone.
Other formulations:
It can also be used with ingredients such as niacinamide to enhance the brightening effect, or with glycolic acid to improve skin texture.

 

Reference

[1]. Effects of trans-4-(aminomethyl) cyclohexanecarboxylic acid/potassium azeloyl diglycinate/niacinamide topical emulsion in Thai adults with melasma: a single-center, randomized, double-blind, controlled study

PMID 24688154; DOI 10.1016/s0011-393x(10)80001-3; Current therapeutic research, clinical and experimental 2010 Dec; 71(6):345-59.

 

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