IDRA21

IDRA21

Details
7-Chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine S,S-dioxide
CAS: 22503-72-6
Molecular formula: C8H9ClN2O2S
Molecular weight: 232.69
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Category
Active Pharmaceutical Ingredients
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Description
Technical Parameters

Product Overview

IDRA-21 is a potent, investigational ampakine compound that acts as a positive allosteric modulator of the AMPA receptors in the brain. By enhancing excitatory neurotransmission, it significantly promotes long-term potentiation (LTP), making it a highly sought-after research ingredient for cognitive enhancement, memory optimization, and the development of therapeutics for age-related cognitive impairment.

Compared to first-generation ampakines (such as Aniracetam), IDRA-21 exhibits vastly superior efficacy, primarily due to its significantly longer half-life and extended duration of biological activity.

 

Technical Specifications (Certificate of Analysis)

Testing items

Specifications

Results

Appearance

White to off-white powder

Conforms

Identification(1HNMR)

Conforms to structure

Conforms

Purity(HPLC, area%)

NLT 99.0%

99.48%

Total impurities

NMT1.0%

0.52%

Water content (Karl-Fischer)

NMT1.0%

0.45%

Residue on ignition

NMT0.2%

0.04%

Heavy metals

NMT20ppm

Conforms

Residue solvents

Acetonitrile

NMT410ppm

Not detected

Ethanol

NMT5000ppm

Not detected

N-heptane

NMT5000ppm

Not detected

Conclusion

This product conforms to the specifications

Core Mechanism & Research Benefits

  • AMPA Receptor Positive Modulation: IDRA-21 selectively targets and modulates AMPA receptors, increasing the strength of synaptic connections involved in learning and neuroplasticity.
  • Advanced Cognitive Enhancement: Widely documented in preclinical research to dramatically improve memory retention, focus, and accelerated learning curves.
  • Extended Half-Life Advantage: Offers sustained cognitive support with a prolonged window of activity, reducing the required dosing frequency compared to traditional, short-lived nootropic compounds.
  • Neuroprotective Potential: Holds promising therapeutic implications for researching age-related cognitive decline, dementia, and brain barrier recovery pathways.

Storage & Commercial Applications

  • Target Industries

Primarily utilized as an active ingredient in cognitive wellness research, neurological pharmaceutical development, and premium, high-end nootropic supplement formulations.

  • Storage & Handling Conditions

Store in a tightly sealed container, protected from direct light, moisture, and heat. Keep at room temperature or in a cool, dry chemical storage environment to preserve maximum structural stability.

 

IDRA21

IDRA21

IDRA21

IDRA21

IDRA21

IDRA21

 

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