Melatonin is a hormone produced by the pineal gland in the brain that regulates the body's biological clock and induces natural sleep.
Its secretion is affected by light: it increases when it's dark and decreases when it's light.
In addition, melatonin secretion decreases with age.
Melatonin has a hypnotic effect. But the effect varies from person to person.
If you have trouble falling asleep due to jet lag, night shifts, irregular work and rest, melatonin may help you adjust your biological clock to a certain extent.
Some chronic diseases can interfere with sleep, such as chronic fatigue syndrome, fibromyalgia, Alzheimer's disease, depression, etc. Melatonin can also be used as a regular supplement for these people.
Our company specializes in the production of custom supplements in various dosage forms.Melatonin powder, tablets and supplement are available.
Prius has a cGMP factory in China and has passed GMP, ISO, HALAL, and KOSHER certifications to ensure product quality.
Are there side effects to melatonin?
So, will there be any side effects to the body if melatonin is used all the time?
Researchers from the UK, the US and France recently published a clinical study showing that melatonin is effective in improving sleep disorders and has no obvious side effects compared to placebo over a two-year period.
However, some studies have also shown that taking melatonin may have some adverse reactions: including drowsiness, headache, dizziness, nausea, and some gastrointestinal reactions.
In the Chinese health food raw material catalog, the recommended dosage of melatonin is 1~3mg/d. Melatonin is a prescription drug in the UK.
It is recommended to start with a small dose of 1mg or even lower, and the daily dosage of melatonin is not recommended to exceed 3mg.
Melatonin supplement dosage forms include:
Soft candies, which have a good taste, controllable dosage, and no psychological burden of taking medicine, are suitable for people with dysphagia.
Tablets, with controllable dosage, are convenient for adults to take.
Quick-dissolving lozenges, suitable for people with dysphagia, help to fall asleep quickly, and have controllable dosage.
Sustained-release tablets, suitable for people who often wake up in the middle of the night, with controllable dosage. Sustained-release tablets will prolong the release and absorption time of the active ingredients in the body. Melatonin sustained-release tablets will not increase bioavailability, but can maintain the level of melatonin in the blood for a longer period of time.
Soft capsules, with controllable dosage.
Chewable tablets, suitable for people with dysphagia, have a good taste.
Drops, suitable for people with dysphagia, suitable for starting with a small dose.
In addition to melatonin ingredients, some products will add vitamin B6, theanine, valerian, 5-HTP, GABA and other ingredients that help sleep.
There are many reasons for insomnia, and melatonin is just one of the ways to help us adjust our sleep. Before taking supplements, first consider whether your lifestyle and sleeping habits are scientific.
If you choose to use supplements, it is recommended to start with a small dose and take it as needed.
Reference
[1]. Sleep, Growth, and Puberty After Two Years of Prolonged-Release Melatonin in Children With Autism Spectrum Disorder. J Am Acad Child Adolesc Psychiatry. 2020 Jan 23. pii: S0890-8567(20)30034-4.
[2]. HuajunXu,ChujunZhang,YingjunQian,et al.Efficacy of melatonin for sleep disturbance in middle-aged primary insomnia: a double-blind, randomised clinical trial[J].Sleep Medicine,2020,(76):113-119.
