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Customized Rhodiola Rosea extract powder:Plant sources,Pharmacological Actions,compound,chemical composition

Jun 01, 2022

Rhodiola root(also known as Arctic root, golden root) genus crassulaceae plants, which are native to the Arctic Circle of eastern Siberia. Rhodiola is widely distributed throughout the polar circles and the multi-mountain regions of Europe and Asia. It mostly grows from 11000 to 18000 feet above sea level. Rhodiola sachalinensis was classified as an adaptive agent by Soviet scientists because of its efficacy in increasing the ability of various chemical, biological and physical stresses. The term "adaption" originated in 1947 and was put forward by Lazarev, a Soviet scientist. He defined an "adaption" as a drug that can neutralize adverse physical, chemical, or biological stresses by producing nonspecific resistance. Rhodiola has been intensively studied in the Soviet Union and Scandinavia for more than 35 years. Similar to other plant adaptogens studied by Soviet scientists, Rhodiola extract has led to beneficial changes in a variety of physiological functions in different fields, including neurotransmitter levels, central nervous system activity, and cardiovascular function.

Customized Rhodiola Rosea extract powder Plant sources

Customized Rhodiola Rosea extract powder: Plant sources 

Rhodiola Rosea extract powder is a natural extract from Rhodiola crenata, which is refined, concentrated, and dried. It is very soluble in water, methanol, ethanol, and ether. Relatively stable to heat.

Customized Rhodiola Rosea extract powder: Pharmacological Actions 

1. Anti-fatigue effect

Oral Rhodiola kirilowii prolonged pole climbing time, swimming time, and loaded swimming time in mice, which Can shorten the time required for recovery after fatigue and improve enzyme, RNA, and protein levels to allow the muscle to recover as soon as possible after fatigue.

2. Effects on central nervous mediators

Salidroside normalized the serotonin content under swimming conditions, i.e., either corrected or reached normal levels in neu - Ronal mediators of sedation. Injection of salidroside (30 – 300 mg/kg) into mice reduced serotonin levels.

3. Antihypoxic effect

Oral administration of the extracts of salidroside alfredii, Rhodiola kirilowii caused the test animals to exhibit marked resistance to various patterns of hypoxia, the effects of which were stronger than those of ginseng and acanthopanax senticosus.

Pharmacological Actions

4. Antitumor

Salidroside did inhibit S180 cells to some extent, and this effect was enhanced with increasing concentrations in the nontoxic side dose range. Continuous oral administration of salidroside extract decreased the extent of carcinogenic damage to the small intestinal wall in mice by rhizobacteria and increased the body's anti-cancer ability.

5. Detoxification

Salidroside antagonized strychnine poisoning and increased the survival of mice by 50% after strychnine poisoning; Also antagonizes Corynebacterium toxin and is able to counteract various bacterial toxins such as tetanus, increasing survival time or survival of mice administered spirits, sodium cyanide, and sodium nitrite.

The root of Rhodiola contains 6 different compounds 

1•Phenylpropanoids: rosavin, rosin, rosarin

2•Phyenylethanolo derivatives: salidroside (Rhodiola side), tyrosol

3•Flavonoids: rodiolin, rodionin, rodiosin, acetylrodalgin, tricin

The root of Rhodiola contains six different compound

4•Monoterpernes: rosiridol, rosiridin

5•Triterpenes: daucosterol, beta-sitosterol

6•Phenolic acids: chlorogenic and hydroxycinnamic, gallic acids.

At present, Rhodiola extracts that have been put into production and applied in a large number of conventional standardization include rose Rhodiola extract and Rhodiola crenulata extract.

Customized Rhodiola Rosea extract powder: chemical composition

1. Phenolic and cyanogenic glycosides:rhodiocyanoside、lotaustralin、sacranosides、rhodioloside、ke np oside、heterodendrin and tyrosol.

2. Flavonoids: catechins,rodiolin, proanthocyanidins,rodiosin、acetylrodalgin, and tricin.

3.Ter penoids:daucosterol,beta-sitosterol,rosiridol and rosaridin.

4. Organic acid: chlorogenic, hydroxycinnamic,caffeic, and gallic acids.

Customized Rhodiola Rosea extract powderchemical compositio

In addition, other ingredients also contain tannins, volatile oil, fat, vitamins, human essential amino acids, organic germanium, iron, titanium, cobalt, molybdenum, manganese, and other active trace elements. At present, the research results show that although the same species of Rhodiola are plants of Rhodiola, the chemical components of different species of Rhodiola have great differences in their pharmacological effects.

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