Xi'an Prius Biological Engineering Co.,Ltd
Mail: info@prsbiotech.com
Address: Room 0836, Euro-Asia International Building A, Ouya avenue, Xi'an, Shaanxi Province, China
Zip code: 710038
Product:Febrifugine/Dichroa Febrifuga powder
CAS:24159-07-7
Molecular formula:C16H19N3O3
Molecular weight:301.344
Accurate Mass:301.142642
Percentage Composition:C 63.77%; H 6.35%; N 13.94%; O 15.93%
Febrifugine is a quinazolinone alkaloid first isolated from the Chinese herb Dichroa febrifuga, but also found in the garden plant Hydrangea.Laboratory synthesis of febrifugine determined that the originally reported stereochemistry was incorrect.
Febrifugine has antimalarial properties and the synthetic halogenated derivative halofuginone is used in veterinary medicine as a coccidiostat. Other synthetic febrifugine derivatives have been used against malaria, cancer, fibrosis, and inflammatory disease.
Product: | Febrifugine/Dichroa Febrifuga powder | ||
CAS: | 24159-07-7 | ||
Molecular formula: | C16H19N3O3 | ||
Molecular weight: | 301.344 | ||
Accurate Mass: | 301.142642 | ||
Percentage Composition: | C 63.77%; H 6.35%; N 13.94%; O 15.93% | ||
Physical Description: | White crystal | ||
Biological Source: | Dichroa febrifuga | ||
Biological Use/Importance: | Shows high degree of antimalarial activity,antipyretic and emetic activities | ||
Melting Point: | Mp 139-140℃. Mp 154-156℃(dimorph.) | ||
Optical Rotation: | [α]25D +6 (c, 0.5 in CHCl3) (c, 0.5 in EtOH) | ||
Partition Coefficient (Calculated): | Log P-0.33 (calc) | ||
Assay: | ≥ 98% | ||
USES: | Used for content determination of/identification/pharmacology experiment, etc | ||
Storage conditions: | 2-8°C refrigerated, sealed, avoid light | ||
The period of validity: | 2 years | ||
Availability: | The spot |
COA of Febrifugine:
Item | Standard | Test Results | |
Identification | A.H-NMR:Comply with the structure | Complies | |
B.LC-MS:Comply with the structure | Complies | ||
C.The IR spectrum of sample should be identical with that of reference standard; | Complies | ||
D.HPLC-ESI-MS The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay. | Complies | ||
Crystallinity | meets the requirements. | Complies | |
Loss on drying | ≤2.0% | 0.19% | |
Heavy metals | ≤10 ppm <10ppm | ||
Water | ≤1.0% | 0.1% | |
Sulphated ash | ≤0.5%, determined on 1.0 g. | 0.009% | |
Related substances | Unspecified impurities: for each impurity | ≤0.10% | <0.10% |
Total Impurity | ≤0.5% | 0.18% | |
Purity | ≥99.0% | 99.7% | |
Assay | 99.0%~101.0% (anhydrous substance). | 99.8% | |
Microbiological Analysis | |||
Total plate count | ≤1000cfu/g | Complies | |
Yeast and Moulds | ≤100cfu/g | Complies | |
E. Coli. | Absent | Negative | |
Salmonella | Absent | Negative | |
S.aureus | Absent | Negative | |
Storage | Preserve in well-closed, light-resistant and airtight containers. | Complies | |
Storage&Packing:
Storage: Store in cool & dry place, Keep away from strong light and heat.
Shelf life: 24Months when properly stored.
Packing: 10g/one bag
1kg/one bag
25kgs/drum
Or according to customers' request.
FAQ:
Q1.Can I get some samples?
A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2: How to start orders or make payments?
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union or Paypal or Escrow(Alibaba).
Q3: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.
You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q4:What’s your MOQ?
A:Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
Q5: How about delivery leadtime?
A:About 3-5 days after payment confirmed. (Chinese holiday not included)
Q6:Is there a discount?
A:Different quantity has different discount.
