Xi'an Prius Biological Engineering Co.,Ltd
Address:Room 0836,Euro-Asia International Building A,Ouya avenue ,Xi'an,Shaanxi Province ,China.
Zip code:710038
Phone:+86-4006670006
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Dichroa Febrifuga Powder is extracted from the dried roots of Dichroa Febrifuga. It can used for content determination of/identification/pharmacology experiment, etc
Send InquiryChat NowDichroa Febrifuga Powder
Dichroa Febrifuga Powder is extracted from the dried roots of Dichroa Febrifuga. It contains a variety of alkaloids, such as α-, β-, γ-dichroine, dichroidine, 4-quinazolone), dicnrin A, umbeli-ferone), and dictirin B. α-, β-, γ-dichroine have special effects on malaria. γ-dichroine has the strongest anti-malarial effect, and its effect is about 98-152 times that of quinine hydrochloride. β-dichroine is 89-122 times that of quinine, and the total alkali is about 26 times that of quinine.
1. Has an inhibitory effect on influenza A virus (PR8).
2. Alkaloids have a strong inhibitory effect on malaria parasites.
3. Has antihypertensive effect
4. Can stimulate the gastrointestinal tract and act on the vomiting center, causing vomiting.
| Product: | Dichroa Febrifuga Powder | |||||||||
| CAS: | 24159-07-7 | |||||||||
| Molecular formula: | C16H19N3O3 | |||||||||
| Molecular weight: | 301.344 | |||||||||
| Accurate Mass: | 301.142642 | |||||||||
| Percentage Composition: | C 63.77%; H 6.35%; N 13.94%; O 15.93% | |||||||||
| Physical Description: | White crystal | |||||||||
| Biological Source: | Dichroa febrifuga | |||||||||
| Biological Use/Importance: | Shows high degree of antimalarial activity,antipyretic and emetic activities | |||||||||
| Melting Point: | Mp 139-140℃. Mp 154-156℃(dimorph.) | |||||||||
| Optical Rotation: | [α]25D +6 (c, 0.5 in CHCl3) (c, 0.5 in EtOH) | |||||||||
| Partition Coefficient (Calculated): | Log P-0.33 (calc) | |||||||||
| Assay: | ≥ 98% | |||||||||
| USES: | Dichroa Febrifuga Powder can used for content determination of/identification/pharmacology experiment, etc | |||||||||
COA of Febrifugine:
| Item | Standard | Test Results | |
Identification | A.H-NMR:Comply with the structure | Complies | |
B.LC-MS:Comply with the structure | Complies | ||
C.The IR spectrum of sample should be identical with that of reference standard; | Complies | ||
D.HPLC-ESI-MS The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay. | Complies | ||
Crystallinity | meets the requirements. | Complies | |
Loss on drying | ≤2.0% | 0.19% | |
Heavy metals | ≤10 ppm | <10ppm | |
Water | ≤1.0% | 0.1% | |
Sulphated ash | ≤0.5%, determined on 1.0 g. | 0.009% | |
Related substances | Unspecified impurities: for each impurity | ≤0.10% | <0.10% |
Total Impurity | ≤0.5% | 0.18% | |
Purity | ≥99.0% | 99.7% | |
Assay | 99.0%~101.0% (anhydrous substance). | 99.8% | |
