Leech Extract Hirudin

Hirudin is one component extracted from (Leech) and its salivary glands. Hirudin is the most signification  a variety of active ingredients and most study. Hirudin is composed of 65-66 amino acids of small molecular protein (peptide) The Leech is rich in hirudin, hirudin has a strong inhibitory effect on thrombin, so far found the strongest thrombin natural specific inhibitor.

1. Anticoagulant effect: It can directly inhibit the activity of thrombin and block the formation of blood clots. Combined with thrombin, it prevents the conversion of fibrinogen to fibrin, thereby preventing blood clotting. This makes it a powerful anticoagulant.

2. Thrombolytic effect: In addition to inhibiting the formation of thrombin, it can also activate plasmin and promote the dissolution of thrombus. This is of great significance for the prevention and treatment of thrombosis in diseases such as heart disease and stroke.

3. Anti-inflammatory effect: Studies have shown that it has a certain anti-inflammatory effect. It can inhibit the activation and chemotaxis of inflammatory cells in the inflammatory response, thereby reducing the release of inflammatory mediators and relieving inflammatory symptoms.

4. Protect tissue damage: It has a certain antioxidant effect and can reduce tissue oxidative stress and damage. In addition, it also has the effect of inhibiting platelet aggregation and protecting endothelial function, thus helping to protect the vascular intima from damage.

5. Anti-tumor effect: some studies have shown that it may have an inhibitory effect on tumor growth and metastasis. It is believed to achieve anti-tumor effects by interfering with angiogenesis, inhibiting platelet aggregation, and modulating the interaction between tumor cells and stroma.

6. Antibacterial effect: Some studies have shown that it has the effect of inhibiting bacterial growth and adhesion. It may play an antibacterial role by interfering with bacterial thrombin generation and adhesion molecules.

7. Protection of organ function: It is considered to have the potential to protect the function of organs such as the heart, liver and kidney. It may play a protective role by reducing inflammation, inhibiting oxidative stress, and improving blood flow, among other things.

8. Anti-thrombotic recanalization: It can not only block the formation of thrombus, but also promote the recanalization of thrombus through a certain mechanism. This has important implications for the treatment of vascular obstructive diseases such as cardiovascular disease.

1. Treatment of blood coagulation diseases: it is a powerful anticoagulant, which can be used to prevent and treat diseases related to thrombosis, such as myocardial infarction, stroke, deep vein thrombosis, etc. It can inhibit the activity of thrombin, block the formation of thrombus, and promote the dissolution of thrombus.

2. Minimally invasive surgery and replantation surgery: It can be used for some minimally invasive surgery that requires anticoagulant treatment, such as angioplasty, vascular stent implantation, etc. In addition, in tissue replantation surgery, it can help promote the patency of reconnected blood vessels, reducing ischemic damage and thrombosis.

3. Hemodialysis: It is also used in hemodialysis. For those patients who need long-term hemodialysis treatment, in order to avoid blood coagulation in the dialyzer, it can be added to the blood to play an anticoagulant effect.

4. Clinical trials and research: It is also used in some clinical trials and research. It can be used as an anticoagulant in the processing of blood samples to keep the original state of the blood samples.

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We have our own plant extraction workshop and OEM aseptic workshop.

The company has strong technical force and experienced production staff. The company has 6 sets of 6m3 modern multi-functional extraction equipment, 4 sets of 5m3 reactors, 7 sets of external circulation evaporation and concentration equipment with an evaporation capacity of 1500kg/h, 4 sets of chromatographic columns with a volume of 2m3, and an evaporation capacity of 250kg/h spray One set of drying tower, one set of rectifying alcohol 2000kg/h rectifying tower, 400㎡ of Class D clean area.

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We have participated in the domestic professional exhibition of plant extracts, and we are going to participate in the western United States exhibition in October 2023. Welcome to visit us.

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