In 1819, Danish chemists first isolated piperine from pepper fruit. Tetrahydropiperine (THP), a hydrogenated derivative of piperine, is an oil-soluble absorption enhancer that helps promote the penetration and absorption of the required active ingredients in the skin and tissues. The added amount of 0.01-0.05% has a significant effect. This product is used in skin care products, food and medicine.
About our factory:
We have our own plant extraction workshop and OEM aseptic workshop.
The company has top R&D level and experienced technical staff. The factory has 6 sets of 6m3 modern multi-functional extraction equipment, 4 sets of 5m3 reactors, 7 sets of external circulation evaporation and concentration equipment with an evaporation capacity of 1500kg/h, 4 sets of chromatographic columns with a volume of 2m3, and an evaporation capacity of 250kg/h spray One set of drying tower, one set of rectifying alcohol 2000kg/h rectifying tower, 400㎡ of Class D clean area.
| Product Name: | Black Pepper Extract | Country of Origin: | P. R. China |
| Botanic Name: | Piper nigrum L. | Type of extraction: | Grain Alcohol |
| Plant Part: | Seed | Active Ingredient: | piperine |
| Analysis Item | Specification | Result | Test Method |
| Active Ingredeints | |||
| Piperine | >98 % | 98.07 % | HPLC |
| Physical Control | |||
| Appearance | off white powder | Complies | Visual |
| Odor | Characteristic | Complies | Olfactory |
| Taste | Special Sour | Conforms | Organoleptic |
| Sieve Analysis | 100% pass 80mesh | Complies | 80 mesh Screen |
| Loss on Drying | 5% Max | 3.21% | USP32<561> |
| Ash | 5% Max | 2.58% | USP32<731> |
| Chemical Control | |||
| Arsenic (As) | NMT 1 ppm | 0.05 ppm | USP32<231> |
| Cadmium(Cd) | NMT 0.5 ppm | 0.14 ppm | USP32<231> |
| Lead (Pb) | NMT 0.5 ppm | 0.03 ppm | USP32<231> |
| mercury (Hg) | NMT 0.1 ppm | 0.02 ppm | USP32<231> |
| Residual solvents | Meet USP32 Requirments | Conforms | USP32<467> |
| Heavy Metals | 10 ppm Max | Complies | USP32<231> |
| Residual pesticides | Meet USP32 Requirments | Conforms | USP32<561> |
| Microbiological Control | |||
| Total Plate Count | 10000 cfu/g Max | Complies | USP34<61> |
| Yeast & Mold | 1000 cfu/g Max | Complies | USP34<61> |
| E.Coli | Negative | Complies | USP34<62> |
| Staphylococcus | Negative | Conforms | USP34<62> |
| Staphylococcus aureus | Negative | Complies | USP34<62> |
| Conclusion: | Meet the USP standard | ||
TetraHydroPiperine, THP is a natural active ingredient extracted from black pepper and is a safe and natural penetration enhancer.
Compared with traditional penetration enhancers, THP has the advantages of being natural, effective at low concentrations, and non-irritating, so it is widely used in the pharmaceutical and cosmetic industries.
A very small amount of tetrahydropiperine (0.01-0.1%) can effectively promote the absorption and utilization of active ingredients by the skin.
The penetration-enhancing mechanism of THP: 1) Improve the fluidity of the lipid bilayer and promote the diffusion of active ingredient molecules in the lipid bilayer; 2) Enhance the affinity of the cell membrane for the active ingredient.
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