Nicotinamide Riboside Supplement

NR is a precursor of the important cofactor NAD+, and it is inextricably linked to NAD+.
Researchers have found that NR turns into NAD+ faster than other forms of vitamin B3, which means that nicotinamide riboside supplement is beneficial for individuals who are deficient in NAD+. Therefore, it can be used as a functional ingredient in anti-aging and health-promoting supplements.Taking NR supplements is the most common way to increase NAD+ levels.

Our formula ensures high levels of absorbability and bioavailability, with close to 100% absorption, and is tested for potency and safety.

Optimized formula:

1. Nicotinamide Riboside + Trans-Resveratrol
2. NR+Resveratrol+Quercetin
3. Nicotinamide Riboside + Berberine + Resveratrol + Spermidine + Fisetin + Quercetin + Apigenin

4. Resveratrol + Berberine + Fisetin+ Quercetin+Grape Seed Extract+ Milk Thistle+ Green Tea Extract

On the one hand, NAD+ is a very important coenzyme in the redox reaction of organisms, helping to convert adenosine diphosphate (ADP) into adenosine triphosphate (ATP). On the other hand, NAD+ is a cosubstrate for a variety of enzymatic reactions.

1. At the cellular level, after NR enters the cell, it can be phosphorylated by NR kinases NRK1 and NRK2 to become CAS 1094-61-7, or deribosylated to become NAM under the action of purine nucleoside phosphorylase.

Several clinical studies have confirmed that NR is beneficial to metabolism, and supplementing CAS 1094-61-7 or NR can reverse aging and prolong life.

2. Researchers have observed that taking 1000mg NR per day can increase NAD in the brain. The authors of the study believe that NR treatment can increase NAD and its metabolites in the brain, or improve Parkinson's disease.
3. A study published in the European Journal of Nutrition in 2019 found that taking nicotinamide riboside supplement can improve the physical function of the elderly and reduce oxidative stress. It is more effective for the elderly population.

Reference

[1]. Lee HJ, Yang SJ. Supplementation with nicotinamide riboside reduces brain inflammation and improves cognitive function in diabetic mice. Int J Mol Sci 2019;20(17). pii: E4196. View abstract.

[2]. Yoshino J, Baur JA, Imai SI. NAD+ intermediates: the biology and therapeutic potential of CAS 1094-61-7 and NR. Cell Metab 2018;27(3):513-28. View abstract.