Through a strict production process, the raw materials of berberine hydrochloride are crushed and then extracted with sulfuric acid, the crude product is precipitated by hydrochloric acid and then refined to obtain the finished product. The finished product is a yellow powder with a slight smell and extremely bitter taste. It is soluble in water but hardly soluble in benzene, ether, and chloroform. It can be used as an antibacterial drug in clinical applications.

| Analysis Item | Specification | Result | Test Method |
| Berberine | NLT 95% | 95.12% | HPLC |
| Appearance | Fine Yellow Powder | Complies | Visual |
| Odor | Characteristic | Complies | Olfactory |
| Sieve Analysis | 100% pass 80mesh | Complies | 80 mesh Screen |
| Loss on Drying | 5% Max | 2.87% | USP32<561> |
| Ash | 5% Max | 1.13% | USP32<731> |
| Arsenic (As) | NMT 1ppm | 0.12ppm | USP32<231> |
| Cadmium(Cd) | NMT 0.5ppm | 0.13ppm | USP32<231> |
| Lead (Pb) | NMT 0.5ppm | 0.06ppm | USP32<231> |
| mercury (Hg) | NMT0.1ppm | 0.03ppm | USP32<231> |
| Residual solvents | Meet USP32 Requirments | Conforms | USP32<467> |
| Heavy Metals | 10ppm Max | Complies | USP32<231> |
| Residual pesticides | Meet USP32 Requirments | Conforms | USP32<561> |
| Total Plate Count | 1000cfu/g Max | Complies | USP34<61> |
| Yeast & Mold | 100cfu/g Max | Complies | USP34<61> |
| E.Coli | Negative | Complies | USP34<62> |
| Staphylococcus | Negative | Conforms | USP34<62> |
| Staphylococcus aureus | Negative | Complies | USP34<62> |
| Conclusion: | Meet the USP standard | ||

1. The extract of Rhizoma Coptidis has the effects of clearing heat and detoxification, clearing heat and detoxifying;
2. Coptis extract has the function of relaxing the vascular smooth muscle and exciting other smooth muscles, such as bladder muscle, bronchial muscle, and gastrointestinal muscle.
3. Berberine hydrochloride, an extract of Rhizoma Coptidis, has antibacterial and antibacterial effects.
4. It is mainly used to treat bacterial dysentery, lung abscess, brucellosis, acute tonsillitis, maxillary sinusitis, oral and maxillofacial inflammation.
5. It can be used to treat gastroenteritis, etc.

It can be used in clinical applications as well as in the field of health care products.





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