
Creatine is a compound made of arginine, glycine, and methionine that combines with phosphate molecules to create creatine phosphate. Creatine monohydrate is the supplement form of creatine and is the most extensively researched and clinically effective form of creatine. Optimum nutrition creatine monohydrate powder is slightly soluble in water and insoluble in ethanol and ether.
Creatine phosphate is an energy reserve substance used to maintain ATP levels during high-intensity exercise. Creatine monohydrate can store more ATP.
COA of Creatine Monohydrate
| Items | Specification | Test results |
| Appearance |
White crystals or crystalline powder
|
Conformed
|
|
Assay(Titration)
|
≥ 99.5%
|
99.99% |
|
Creatinine
|
≤ 50PPM
|
41PPM |
|
Dicyanamide
|
≤ 50PPM | 39PPM |
|
Loss On Drying
|
≤ 12%
|
11.5% |
|
Residue on ignition
|
≤ 0. 1%
|
0.01% |
|
Iron
|
≤ 10ppm
|
<10ppm |
|
Sulphate
|
≤ 0.1%
|
<0.1% |
|
Heavy metals(Pb)
|
≤ 5ppm
|
< 5PPM |
|
Arsenic(As)
|
≤ 1ppm
|
< 1PPM |
|
Lead(Pb)
|
≤ 1ppm
|
<1PPM |
|
Mercury(Hg)
|
≤ 0.1ppm
|
<0.1PPM |
|
Cadmium(Cd)
|
≤ 1ppm
|
< 1PPM |
|
Mesh(M)
|
200M
|
200M
|
|
Bulk Density
|
≥ 0.43g/ml
|
0.53g/ml |
|
Tapped Density
|
≥ 0.55g/ml
|
0.64g/ml |
|
Total Plate Count(CFU/g)
|
≤ 1000 CFU/g
|
Conformed |
|
Mould & Yeast
|
≤ 100CFU/g
|
Conformed |
|
E.coli
|
Negative
|
Conformed |
|
Salmoneaal
|
Negative | Conformed |
|
Staphylococcus Aureus
|
Negative | Conformed |

Benefits of creatine monohydrate
1. Optimum nutrition Creatine monohydrate powder supports better muscle mass and is suitable for both men and women. Creatine monohydrate (CM) is currently the most effective nutritional supplement for athletes to maintain high-intensity exercise capabilities during training.
Solution:
Creatine monohydrate and probiotics can be formulated. The tasteless creatine powder is micronized through a specific production process, making it easier to add to product formulas and more easily absorbed and utilized by the human body.
Most studies show that oral administration of creatine monohydrate increases creatine concentrations in the blood within 3-4 hours, thereby promoting creatine absorption into tissues via diffusion and creatine transporters. Short-term supplementation with creatine monohydrate can increase muscle reserves by 20-40% and exercise performance by 5-10%. Supplementing creatine monohydrate during training can promote increases in muscle mass, strength, and athleticism.
In addition, its potential in muscle health and cognitive health has been tapped, which has also promoted the rapid growth of creatine in overseas markets. Creatine will be a great ingredient for the sports nutrition market.
2. Creatine monohydrate has a positive impact on cognitive function. Some studies have shown that supplementing with creatine monohydrate can increase levels of creatine phosphorylation in the brain, thus having a positive impact on cognitive function. It is believed to improve learning ability and memory.
Altered brain bioenergetics and mitochondrial dysfunction are associated with depression, particularly with CK, ATP, and inorganic phosphate. Creatine supplementation has been shown to significantly enhance Pi levels.

Optimum nutrition creatine monohydrate powder is available as dietary supplements and are regulated by the U.S. Food and Drug Administration (FDA).
In the United States, creatine monohydrate is GRAS certified and can be used in the formulation of functional drinks, protein powders, milkshakes, meal replacement powders, imitation meat products, and mixed drinks.
Studies have shown that creatine is beneficial in aging and muscle loss in the elderly, which has caused older consumers to also pay attention to creatine products. The creatine products already on the market are designed for people over the age of 55. , providing them with aging support.
Reference
[1].Banerjee, B., Sharma, U., Balasubramanian, K., Kalaivani, M., Kalra, V., and Jagannathan, N. R. Effect of creatine monohydrate in improving cellular energetics and muscle strength in ambulatory Duchenne muscular dystrophy patients: a randomized, placebo-controlled 31P MRS study. Magn Reson.Imaging 2010;28(5):698-707.
[2]. Chilibeck, P. D., Stride, D., Farthing, J. P., and Burke, D. G. Effect of creatine ingestion after exercise on muscle thickness in males and females. Med Sci Sports Exerc 2004;36(10):1781-1788.








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