Retinoic Acid Powder | 99% High Purity USP Grade | All-Trans Vitamin A Acid Raw Material (CAS 302-79-4)
Key Product Highlights
- High-purity all-trans retinoic acid with typical assay of 99.8%, fully compliant with USP 36 standard
- Large-scale in-house production capacity, stable bulk supply with fast delivery
- Strict impurity control: isotretinoin and related substances far below USP limits
- Samples available for quality verification prior to bulk order
- Full traceable quality control with complete Certificate of Analysis for each batch
Product Overview
Retinoic acid (all-trans retinoic acid, ATRA) is a biologically active derivative of vitamin A acid, with CAS number 302-79-4. Produced by Xian Prius Biological Engineering on a large scale, our retinoic acid appears as a yellow crystalline powder with a minimum purity of 99%, meeting USP 36 quality specifications.
As a core active raw material with cell regulation activity, it is widely used in pharmaceutical R&D, dermatological preparation production and professional personal care formulation. It exerts biological effects by binding to nuclear receptors, and plays an important role in regulating cell growth, differentiation and metabolic processes.
Core Physicochemical Properties
|
Product name |
Retinoic acid |
||||
|
CAS No. |
302-79-4 |
Outer Packing |
25KG/DRUM |
||
|
Production date |
2022.09.05 |
Shelf life |
2024.09.04 |
||
|
Standard adopted |
USP 36 |
||||
|
Items of analysis |
Specification |
Results |
|||
|
Appearance |
Yellow to light-orange crystalline pcwder |
Yellow crystalline powder |
|||
|
Identification |
I.The IR absorption spectrum should corr cspond with reference spectrum 2.Should exhibits maximum absorption at 352nm |
1 .Correspond with reference spectrum 2. Exhibits Maximum absorption at 352nm |
|||
|
Loss on drying |
<0.5% |
0.3% |
|||
|
Residue on igni Ion |
<0.1% |
0.03% |
|||
|
Heavy metals |
<0.002% |
<0.002% |
|||
|
sotretinoin |
<5.0% |
0.1% |
|||
|
Related Substa nces |
<0.5% |
0.26% |
|||
|
Assay (anhydro us) |
97.0%-103.0% |
99.8% |
|||
|
Methanol |
<3000 ppm |
20ppm |
|||
|
Ethyl acetate |
< 5000 ppm |
3000ppm |
|||
|
sopropanol |
< 5000 ppm |
17 ppm |
|||
|
Conclusion |
Qualified |
||||
Core Biological Activities
Retinoic acid exerts regulatory effects on cell growth, differentiation and tissue metabolism by binding to nuclear receptors and modulating gene expression. Its main documented biological activities include:
- Keratinocyte regulation: Regulates epidermal cell proliferation and differentiation, helps loosen keratinized cells and promote epidermal renewal.
- Skin metabolism support: Accelerates skin cell turnover, supports collagen and elastic fiber synthesis, and helps reduce melanin deposition.
- Anti-inflammatory activity: Inhibits inflammatory response and reduces inflammatory cell infiltration.
- Cell differentiation regulation: Plays a key role in regulating normal cell proliferation and differentiation processes.
- Immune modulation: Supports lymphocyte proliferation and activation, contributing to normal immune function.
Main Application Fields
With its broad biological activities, retinoic acid is widely used as a raw material in pharmaceutical and professional personal care industries:
- Dermatological pharmaceutical preparations: Core raw material for topical formulations targeting keratinization disorders and acne-related skin conditions.
- Professional anti-aging skincare: Used in high-end professional anti-aging formulations to support skin renewal and collagen production (subject to local regulatory approval).
- Pharmaceutical R&D & production: Applied in research and production of drugs for hematological diseases, oncology and other therapeutic areas.
- Biomedical research: Used as a reagent for cell biology and developmental biology research.
Compliance Notice
This product is an industrial and laboratory raw material for professional use only. It is NOT intended for direct sale to end consumers, nor for direct oral or topical use without professional formulation. All buyers shall ensure that the use, processing and sale of this product fully comply with the laws, regulations and licensing requirements of their respective countries and regions for pharmaceuticals, cosmetics and related products.
Double polyethylene bags inside, and high-quality standard carton drum outside.
Shipping by express, air, Sea, and some special line to most Countries
We have our own plant extraction workshop and OEM aseptic workshop.
The company has strong technical force and experienced production staff. The company has 6 sets of 6m3 modern multi-functional extraction equipment, 4 sets of 5m3 reactors, 7 sets of external circulation evaporation and concentration equipment with an evaporation capacity of 1500kg/h, 4 sets of chromatographic columns with a volume of 2m3, and an evaporation capacity of 250kg/h spray One set of drying tower, one set of rectifying alcohol 2000kg/h rectifying tower, 400㎡ of Class D clean area.
The company not only has advanced technology and professional equipment, but also has a sound system and strict and professional standards in raw material selection and procurement, ensuring a complete and comprehensive quality control system from raw material procurement to product delivery.
We have participated in the domestic professional exhibition of plant extracts, and we are going to participate in the western United States exhibition in October 2023. Welcome to visit us.
Hot Tags: retinoic acid, China retinoic acid manufacturers, suppliers, factory, Tretinoin Powder, Glycyrrhizin, pro xylane products, proxylane, Glabridin powder, Licorice Extract Powder
