Product Overview

Hydroxypinacolone Retinoate (HPR) is a breakthrough, third-generation cosmetic-grade Vitamin A derivative. Formulated as an ester of all-trans retinoic acid, HPR represents the ultimate alternative to traditional retinol and prescription retinoic acid.

Unlike conventional retinoids that require a multi-step enzymatic conversion in the skin, HPR binds directly to retinoid receptors to trigger cellular renewal. This unique mechanism delivers the maximum anti-aging potency of pure retinoic acid, but with exceptionally high stability and a near-zero irritation profile, making it the perfect star ingredient for premium sensitive-skin anti-aging formulations.

Vitamin A Series Products Available: Vitamin A Derivatives and Retinoic Acid Derivatives
Retinaldehyde
Retinoic acid
Retinyl acetate
Retinyl propionate
Retinyl linoleate
Retinyl retinoate
Retinyl palmitate
Hydroxypinacolone retinoate
Retinyl trimethylsilane
Retinol/saccharomyces polypeptide
Methoxy PEG-12 retinamide
Tocopheryl retinoate

Technical Comparison: HPR vs. Traditional Retinol

Feature	Hydroxypinacolone Retinoate (HPR)	Retinol
Potency	More potent, directly binds to retinoid receptors	Weaker, requires conversion to retinoic acid
Conversion Needed	No conversion needed (active form)	Must convert to retinoic acid in the skin
Irritation	Lower risk of irritation, more tolerable	Higher risk of irritation, redness, and peeling
Stability	More stable in formulations	Less stable, degrades faster
Effectiveness	Faster and more direct effects on wrinkles, pigmentation, and collagen production	Slower effects due to conversion process

HPR

Hydroxypinacolone Retinoate

Item	Specification	Results
Appearance	Yellow crystal	Conform
Odor &Taste	Characteristic	Conform
Assay	≥99%	99.83%
Total impurities	≤1.0%	0.17%
Single impurity	<0.5%	0.09%
Retonic acid residue	≤100ppm	Conform
Loss on Drying	≤0.5%	0.30%
Water content	≤0.1%	0.04%
Scorch residue	≤0.1%	0.06%
Heavy Metals	≤10 ppm	Conform
As	≤0.5 ppm	Conform
Cd	≤1.0 ppm	Conform
Pb	≤1.0 ppm	Conform
Hg	≤0.5 ppm	Conform
Pd	≤0.5 ppm	Conform
TotalPlate Count	≤1000 cfu/g	Conform
Total Yeast &Mold	≤100 cfu/g	Conform
E.Coli	Negative	Absent
Salmonella	Negative	Absent/25g
Staphylococcus	Negative	Absent/25g
Test Result: This product passes the test

Core Dermatological Benefits & Efficacy

Clinical Anti-Aging & Wrinkle Reduction: Accelerates collagen synthesis. Clinical evaluations indicate that topical application of 2% HPR significantly visibly reduces the depth of fine lines and wrinkles in as little as 2 weeks.
Epidermal Renewal & Texture Refinement: Optimizes the metabolic cycle of the stratum corneum, sloughing off dead cells to restore smooth, velvety skin texture.
Advanced Sebum & Acne Regulation: Harmonizes sebaceous gland activity, dramatically decreasing excess oil production and minimizing pore appearance.
Targeted Hyperpigmentation & Brightening: Interrupts melanin transfer, evening out skin tone while fading age spots, sun spots, and post-inflammatory dark marks.
Cellular Differentiation: Enhances the skin's natural barrier defense by stimulating healthy cellular differentiation and epidermal thickening.

One-Stop Supply: Our Complete Retinoid Portfolio

As a premier global supplier of Vitamin A derivatives, we offer an extensive inventory of active ingredients customized for your specific formulation needs:

Advanced Retinoic Acid Derivatives: Hydroxypinacolone Retinoate (HPR), Retinyl Retinoate, Methoxy PEG-12 Retinamide, Tocopheryl Retinoate
Classic Vitamin A Derivatives: Retinol, Retinaldehyde, Retinyl Acetate, Retinyl Propionate, Retinyl Linoleate, Retinyl Palmitate
Biotech Retinoids: Retinol/Saccharomyces Polypeptide, Retinyl Trimethylsilane

Hydroxypinacolone Retinoate