Natural plants are important raw materials for extracting drug ingredients. For example, Catharanthus roseus is a common Chinese medicine.
Tabersonine, Tab is a natural compound isolated from the medicinal plant Catharanthus roseus. It is an important intermediate in the synthesis of two commonly used clinical drugs, vinblastine and vincristine. It plays an important role in the production of drug alkaloids.
1. Anti-inflammatory biological activity. Tab exerts anti-inflammatory function by inhibiting TRAF6 ubiquitination.
2. Used in the field of biosynthesis. As a precursor of the biosynthetic pathway of terpenoid indole alkaloids (TIA).
| Item | Specification | Result |
| Physical control | ||
| Appearance | Brown fine powder | Complies |
| Assay | 20:1 | Complies |
| Odor | Characteristic | Complies |
| Particle Size | 100% pass 80 mesh | Complies |
| Loss on Drying | ≤5.0% | 3.25% |
| Chemical Control | ||
| Total Heavy Metals | ≤10ppm | Complies |
| Ash | ≤1.0ppm | Complies |
| Lead | ≤1.0ppm | Complies |
| Arsenic | ≤1.0ppm | Complies |
| Residue of Pesticide | Complies | |
| Microbiological Tests | ||
| Total Plate Count | ≤1000cfu/g | Complies |
| Yeast&Mold | ≤100cfu/g | Complies |
| E.coil | Negative | Complies |
| Salmonella | Negativev | Complies |
| Staphylococcus | Negative | Complies |
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