Diosgenin Powder

Diosgenin Powder

Details
CAS:512-04-9
Assay:≥95%
Molecular Formula:C27H42O3
Molecular Weight:414.6206
MOQ:1KG
Free sample:available
Capacity:100-200tons
Category
Active Pharmaceutical Ingredients
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Description
Technical Parameters

plant extract description

Diosgenin powder is a type of steroidal saponin distributed in Solanum and Dioscorea plants, and is a natural phytoestrogen. Monocotyledonous Dioscoreae plants are the main sources of diosgenin, and the amount of diosgenin synthesized by monocotyledonous plants is much higher than that of dicotyledonous plants. In the same yeast strain background and using the same yeast culture conditions, it was found that the function of the diosgenin synthesis gene of monocotyledonous plants is much stronger than that of diosgenin synthesis genes of dicotyledonous plants. Diosgenin exists almost 100% in the form of glycosides in plants. Modern research shows that it has anti-inflammatory, antioxidant, anti-diabetic and anti-tumor activities. 

COA

Items

Standard

Results

Appearance

Light yellow or almost white crystalline powder,odorless

Complies

Clarity

Should be clanified in 1% ethanol solution

Complies

Melting Point

≥190℃

195℃-204.5℃

Specific Rotation

+120°~+122°

Complies

Loss on Drying

≤0.5%

0.20%

Assay

≥95.0%(HPLC)

98.08%

Particle Size

100%<16Mesh

100%<16Mesh
83.2%<20Mesh

Other Foreigners

Should not be detected

Complies

Sapogenins in Diosgenin

Should be in accordance with Sigma Standard
Diosgenin

Complies

Conclusion

The items tested conform to the requirements of enterprise standard.

plant extract function

Bulk Diosgenin powder is an important basic raw material for the production of steroid hormone drugs.It is the precursor of more than 200 steroid hormone drugs.

It is known as "medicinal gold" in the pharmaceutical community, and its medicinal worth is enormous.

Ingredient for steroidal medicines in the pharmaceutical sector.
Diosgenin is utilized to synthesize steroid compounds, including pregnenolone, progesterone, and cortisol.
Treatment for hypercholesterolemia inflammation.
Treatment for many types of infections.

Market Trends

Diosgenin from China is a reliable and scarce hormone foundation raw resource on the global market. Throughout the history of the world's pharmaceutical raw materials, it has held a dominant and monopolistic position, accounting for 97% of the total.

Reference

[1]. Chojnacki J. E., Liu K., Saathoff J. M., Zhang S. Bivalent ligands incorporating curcumin and diosgenin as multifunctional compounds against Alzheimer's disease. Bioorganic & Medicinal Chemistry . 2015;23(22):7324–7331. doi: 10.1016/j.bmc.2015.10.032.

[2]. Nazir R., Kumar V., Dey A., Pandey D. K. HPTLC quantification of diosgenin in Dioscorea deltoidea: evaluation of extraction efficacy, organ selection, drying method and seasonal variation. South African Journal of Botany . 2021;138:386–393. doi: 10.1016/j.sajb.2020.12.027.

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