Coptis chinensis is a common traditional Chinese medicine. Berberine is a quaternary ammonium alkaloid isolated from the traditional Chinese medicine Coptis chinensis, which is used for antibacterial, treatment of inflammatory diseases and diabetes.
Our factory supplies synthetic Berberine and Berberine Hydrochloride in the form of powder, granules, customized capsules and tablets. It is popular in the field of supplement health products in Europe and the United States, and the market demand is growing rapidly.
Berberine hydrochloride (HCl) is the salt form of berberine and is the most commonly used form in dietary supplements and medicines. It is more bioavailable than pure berberine. It is more stable, water-soluble, and more easily absorbed by the body.
|
Granules |
Powder & Capsules |
| Feature | Berberine | Berberine Hydrochloride (HCl) |
|---|---|---|
| Chemical Form | Pure berberine (base form) | Salt form (berberine + HCl) |
| Solubility | Low | High |
| Stability | Less stable | More stable |
| Bioavailability | Poor | Better than pure berberine |
| Common in Supplements | Rare | Yes, very common |
| Items | Specification | Test Methods |
| Description | Powder | Organoleptic |
| Color | Yellow | Organoleptic |
| Odor | Odorless | Organoleptic |
| Taste | Bitter | Organoleptic |
| Loss on drying | NMT 12.0% w/w | USP<731> |
| Assay | NLT97.0% | USP |
| Mesh size | 100% passes through #80 mesh | USP<786> |
| Residue on ignition | NMT 0.2% | USP<281> |
| Extraction Ratio | 30:1 | TLC |
| Identification | Corresponds to IR reference spectrum | IR |
| Other alkaloids | Meet USP Requirements | USP |
| Color reaction A | Positive | USP |
| Color reaction B | Positive | USP |
| Color reaction C | Positive | USP |
| Chloride | Positive | USP<221> |
| Extract Solvent | Ethanol/Water | USP |
| Total Heavy Metals | NMT 10 ppm | USP<231> |
| Lead | NMT 0.5 ppm | USP<232> |
| Arsenic | NMT 1 ppm | USP<232> |
| Mercury | NMT 0.1 ppm | USP<232> |
| Cadmium | NMT 1 ppm | USP<232> |
| Total Plate count | NMT 10,000 cfu/g | USP<61> |
| Yeast & Mold | NMT 1000 cfu/g | USP<61> |
| E.coli | Negative | USP<62> |
| Salmonella | Negative | USP<62> |
| Staphylococcus | Negative | USP<62> |
What is berberine hydrochloride used for?
Berberine hydrochloride is widely used to treat inflammatory diseases, gastroenteritis, and bacterial dysentery.
It also has a certain effect on tuberculosis and respiratory tract infections.
Berberine has a certain effect in treating diabetes and lowering blood lipids.
It has the effect of assisting weight loss.
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