Nootropics Tianeptine Sodium Powder for Antidepressant CAS 30123-17-2
Product Name:Tianeptine Sodium
CAS:30123-17-2
MF :C21H24ClN2NaO4S
Grade Standard :Pharmaceutical grade
Specification:98%min
Appearance:Off- white to white powder
All types :Tianeptine Sodium; Tianeptine sulfate,Tianeptine Free Acid
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Tianeptine Sodium Powder is a drug mainly used for the treatment of severe depression, although it may also be used to treat asthma or irritable bowel syndrome. It is a white powder, synthesized through a special chemical process, and its purity can reach 99%. The stock is stable and the quality is guaranteed. At the same time, Tianeptine acid, Tianeptine sulfate, and other products can be provided.
Chemically it is a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e., AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.
Testing Items
Specifications
Results
Appearance
White to yellowish powder, very
hygroscopic.
Off-white powder, very
hygroscopic.
Solubility
Freely soluble In water and methanol and
dichloromethane
Conforms
Identification
By HNMR, To match with working standard
Conforms
It gives a reaction of sodium
Conforms
Impurities A
≤0.1%
Not detected
Related compounds
Any impurity ≤0.1%
0.08%
Total impurities ≤0.4%
0.08%
Residual Solvents
Acetidin≤ 0.5%
Not detected
Dichloromethane≤ 0.06%
Not detected
Methanol≤ 0.3%
Not detected
Acetone ≤ 0.5%
Not detected
Acetonitrile≤0.041%
Not detected
Ethanol≤0.5%
Not detected
N, N-dimethylformamide≤0.088%
Not detected
Water
≤ 5.0%
1.5%
Assay
99.0%-101.0%(On an anhydrous basis)
99.92%
Conclusion
This product conforms to in-house standard
Tianeptine Sodium Powder has antidepressant and anxiolytic (anti-anxiety) properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in the elderly and in those following alcohol withdrawal; such persons can be more sensitive to the adverse effects of psychotropic drugs. Recent results indicate possible anticonvulsant (anti-seizure) and analgesic (painkilling) activity of tianeptine via immediate or downstream modulation of adenosine A1 receptors (as the effects could be experimentally blocked by antagonists of this receptor).
Tianeptine sodium is a tricyclic antidepressant (TCA) because recent studies have shown that Tianeptine exerts antidepressant effects by indirectly altering glutamate receptor activity and releasing BDNF, thereby affecting neuroplasticity.
At the same time, studies have shown that Tianeptine may have possible anticonvulsant (anti-seizure) and analgesic (pain-relieving) activities through direct or downstream modulation of adenosine A1 receptors.
Application
Mainly used in antidepressant, antiepileptic products.
Pharmacology
Tianeptine Sodium Powder is an antidepressant, the animal pharmacological research results show that:
1. Increase the spontaneous activity of pyramidal cells in the hippocampus and accelerate the recovery of their function after inhibition.
2. Increase the reabsorption of serotonin by neurons in the cerebral cortex and hippocampus.
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