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product-description

Tianeptine Sodium Powder is a drug mainly used for the treatment of severe depression, although it may also be used to treat asthma or irritable bowel syndrome. It is a white powder, synthesized through a special chemical process, and its purity can reach 99%. The stock is stable and the quality is guaranteed. At the same time, Tianeptine acid, Tianeptine sulfate, and other products can be provided.

Chemically it is a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e., AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.

product-specification

Testing Items	Specifications	Results
Appearance	White to yellowish powder, very hygroscopic.	Off-white powder, very hygroscopic.
Solubility	Freely soluble In water and methanol and dichloromethane	Conforms
Identification	By HNMR, To match with working standard	Conforms
Identification	It gives a reaction of sodium	Conforms
Impurities A	≤0.1%	Not detected
Related compounds	Any impurity ≤0.1%	0.08%
Related compounds	Total impurities ≤0.4%	0.08%
Residual Solvents	Acetidin≤ 0.5%	Not detected
	Dichloromethane≤ 0.06%	Not detected
	Methanol≤ 0.3%	Not detected
	Acetone ≤ 0.5%	Not detected
	Acetonitrile≤0.041%	Not detected
	Ethanol≤0.5%	Not detected
	N, N-dimethylformamide≤0.088%	Not detected
Water	≤ 5.0%	1.5%
Assay	99.0%-101.0%(On an anhydrous basis)	99.92%
Conclusion	This product conforms to in-house standard

Main-Functions-and-Application

Tianeptine Sodium Powder has antidepressant and anxiolytic (anti-anxiety) properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in the elderly and in those following alcohol withdrawal; such persons can be more sensitive to the adverse effects of psychotropic drugs. Recent results indicate possible anticonvulsant (anti-seizure) and analgesic (painkilling) activity of tianeptine via immediate or downstream modulation of adenosine A1 receptors (as the effects could be experimentally blocked by antagonists of this receptor).

Tianeptine sodium is a tricyclic antidepressant (TCA) because recent studies have shown that Tianeptine exerts antidepressant effects by indirectly altering glutamate receptor activity and releasing BDNF, thereby affecting neuroplasticity.

At the same time, studies have shown that Tianeptine may have possible anticonvulsant (anti-seizure) and analgesic (pain-relieving) activities through direct or downstream modulation of adenosine A1 receptors.