What is the source of octacosanol?

1 Octacosanol is a naturally occurring monobasic fat and the main component of policosanol. In nature, it mainly exists in the wax secreted by the peel or fruit surface of plants. It is recognized worldwide as a safe and effective anti-fatigue functional substance. Products on the website can be customized, capsules or other forms of supplements are available.

Octacosanol is a white powder, tasteless and odorless. It is soluble in hot ethanol and ether, but insoluble in water. In addition, octacosanol is stable to acids, alkalis, reducing agents, light, heat, and is not easy to absorb moisture.

At present, the common methods for purifying this substance mainly include distillation, crystallization, molecular distillation and supercritical CO2 extraction.

1 octacosanol

SPECIFICATIONS	SPECIFICATION	METHOD
APPEARANCE	White powder	Visual
ODOUR	Characteristic	Olfactory
TASTE	Characteristic	Gustatory
PARTICLE SIZE	60-80 mesh	Internal Method
LOSS ON DRYING	≤0.5%	Internal Method
ASH	≤0.1%	Internal Method
BULK DENSITY	0.42-0.52 g/ml	Internal Method
TAPED DENSITY	0.55-0.65 g/ml	Internal Method
MELTING POINT	80 - 83ºC	Internal Method
FATTY ACIDS	<1.5 mgKOH/g	Internal Method
SOLUBILITY	Insoluble in water, soluble in the aliphatic and aromatic compound at 70-80ºC / Insoluble in water, soluble in the aliphatic and aromatic compound at 70-80ºC
*ASSAY (GC)*
Total Alcohols	≥98%	Internal Method
1-Tetracosanol (C-24)	0.0 -3.0%	Internal Method
1-Hexacosanol (C-26)	5.0 -15.0%	Internal Method
1-Heptacosanol (C-27)	0.1 -5.0%	Internal Method
1-Octacosanol (C-28)	60.0 - 68%	Internal Method
1-Nonacosanol (C-29)	0.1 -5.0%	Internal Method
1-Triacontanol (C-30)	5.0 -25.0%	Internal Method
1-Hentriacontanol (C-31)	0.1 -3.0%	Internal Method
1-Dotriacontanol (C-32)	0.1 -10.0%	Internal Method
1-Tetratriacontanol (C-34)	0.0 -5.0%	Internal Method
HEAVY METALS*	≤10 ppm	Internal Method
CADMIUM	≤1 ppm	Internal Method
ARSENIC	≤1 ppm	Internal Method
LEAD	≤0.5 ppm	Internal Method
MERCURY	≤0.1 ppm	Internal Method
TOTAL PLATE COUNT*	≤10000 cfu/g	Internal Method
YEASTS AND MOULD*	≤100 cfu/g	Internal Method
E. COLI*	Negative	Internal Method
SALMONELLA spp*	Negative	Internal Method
Conclusion:	Meet the standard

1 octacosanol

It stimulates the production of ATP and provides energy to cells. It increases physical strength, endurance and energy, especially improves muscle endurance and reaction acuity.
It increases energy metabolism rate and basal metabolic rate.
It enhances muscle function including myocardium.
It may be used as a promising substance for the treatment of sleep disorders.

It has anti-ulcer and anti-inflammatory effects, can effectively reduce the weight of adipose tissue, and inhibit the biosynthesis of cholesterol.
Octacosanol reduces liver damage by increasing glutathione levels, which helps relieve stress.

Octacosanol has a certain protective effect on the nervous system and has a good effect in preventing and treating cell loss in diseases such as Alzheimer's disease.

What is octacosanol used for?

1. As a safe and effective nutritional supplement ingredient. Especially used in sports supplements.
2. Used in biological research and clinical research applications.

Reference

[1]. Enoki T,Sagawa H,Tominaga T,et al. Drugs,foods or drinks with the use of algae-derived physiologically active substances: 0105029 A1 ［P］． U. S. Patent,2003.

[2]. Simonetta Oliaro-Bosso,et al. Ｒegulation of hmgcoA reductase activity by policosanol and octacosadienol,a new synthetic analogue of octacosanol ［J］． Lipids,2009,44( 10) : 907-916.

octacosanol