The main active ingredients of motherwort extract are leonurine and stachydrine hCL.
Motherwort herb extract contains a variety of alkaloids such as leonurine, stachydrine, leonuridine, and leonurine.
Stachydrine Hydrochloride powder is stable in nature, resistant to high temperatures, acid and alkali. It is easily soluble in water, alcohol, and dilute acid, but insoluble in chloroform and ether.
5% is brown powder, and 98% is white powder. Other Alkaloids products are also available.
It has the effects of promoting blood circulation and regulating menstruation, diuresis and swelling, and detoxification.
|
98% |
5% |
| Item | Specification | Result |
|
Appearance |
Off-white powder |
Complied |
|
Odor |
Characteristic |
Complied |
|
Assay(HPLC) |
98.0% |
98.3% |
|
Loss on drying |
≤3.0% |
1.51% |
|
Residue on ignition |
≤3.0% |
0.29% |
|
Heavy metal |
≤10PPM |
Complied |
|
As |
≤2PPM |
Complied |
|
Pb |
≤3PPM |
Complied |
|
Hg |
≤0. 5PPM |
Complied |
|
Total Plate |
<1000CFU/g |
Complied |
|
Yeast & Mold |
<100CFU/g |
Complied |
|
Salmonella |
Negative |
Complied |
|
Negative |
Negative |
Complied |
| Conclusion |
Conform with Specification |
1. Stachydrine hydrochloride has the function of repairing kidney function and can repair glomeruli.
2. This product has the functions of promoting blood circulation and regulating menstruation, contracting the uterus, and can inhibit the occurrence of adenomyosis.
3. Stachydrine hydrochloride can increase coronary artery and myocardial blood flow, reduce myocardial cell necrosis, reduce vascular resistance, improve microcirculation, etc. It is expected to become a good therapeutic drug for cardiovascular system diseases.
4. Stachydrine hydrochloride has anti-myocardial hypertrophy activity and can inhibit the NF-κB signaling pathway.
Inhibit platelet aggregation
5. Motherwort extract can reduce coronary resistance, heart rate and blood output, thereby controlling platelet aggregation and effectively preventing thrombosis.
6. It has been reported that motherwort alkaloids have an excitatory effect on the respiratory center.
1. For biomedical research, For Laboratory Use.
Stachydrine hydrochloride can be used in the study of cardiovascular diseases.
2. Medical field.It can be used as an ingredient of motherwort granules and motherwort capsules or other medicines and health care products.
Reference
[1]. H.-H. Chen, S.-N. Wang, T.-T. Cao, J.-L. Zheng, J. Tian, X.-L. Shan, P. Zhao, W. Guo, M. Xu, C. Zhang, R. Lu
Stachydrine hydrochloride alleviates pressure overload-induced heart failure and calcium mishandling on mice
J. Ethnopharmacol., 248 (2020), Article 112306
[2]. Minghui Chen, et al. Stachydrine hydrochloride inhibits osteoclastogenesis by regulating the NF-κB and p38 signaling pathways to alleviate postmenopausal osteoporosis
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