Tianeptine Free Acid and Tianeptine Sodium Powder CAS 30123-17-2

Tianeptine Free Acid and Tianeptine Sodium Powder CAS 30123-17-2

Product Name:Tianeptine Sodium
CAS:30123-17-2
MF :C21H24ClN2NaO4S
Grade Standard :Pharmaceutical grade
Specification:98%min
Appearance:Off- white to white powder
All types :Tianeptine Sodium; Tianeptine sulfate,Tianeptine Free Acid

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product-description

Tianeptine Sodium Powder is a drug mainly used for the treatment of severe depression, although it may also be used to treat asthma or irritable bowel syndrome. It is a white powder, synthesized through a special chemical process, and its purity can reach 99%. The stock is stable and the quality is guaranteed. At the same time, Tianeptine acid, Tianeptine sulfate, and other products can be provided.

Chemically it is a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e., AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.

product-specification

Testing Items

Specifications

Results

Appearance

White to yellowish powder, very

hygroscopic.

Off-white powder, very

hygroscopic.

Solubility

Freely soluble In water and methanol and

dichloromethane


Conforms


Identification

By HNMR, To match with working standard

Conforms

It gives a reaction of sodium

Conforms

Impurities A

≤0.1%

Not detected


Related compounds

Any impurity ≤0.1%

0.08%

Total impurities ≤0.4%

0.08%





Residual Solvents

Acetidin≤ 0.5%

Not detected

Dichloromethane≤ 0.06%

Not detected

Methanol≤ 0.3%

Not detected
Acetone ≤ 0.5%Not detected

Acetonitrile≤0.041%

Not detected

Ethanol≤0.5%

Not detected

N, N-dimethylformamide≤0.088%

Not detected

Water

≤ 5.0%

1.5%

Assay

99.0%-101.0%(On an anhydrous basis)

99.92%

Conclusion

This product conforms to in-house standard

Main-Functions-and-Application

Tianeptine Sodium Powder has antidepressant and anxiolytic (anti-anxiety) properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in the elderly and in those following alcohol withdrawal; such persons can be more sensitive to the adverse effects of psychotropic drugs. Recent results indicate possible anticonvulsant (anti-seizure) and analgesic (painkilling) activity of tianeptine via immediate or downstream modulation of adenosine A1 receptors (as the effects could be experimentally blocked by antagonists of this receptor).

Tianeptine sodium is a tricyclic antidepressant (TCA) because recent studies have shown that Tianeptine exerts antidepressant effects by indirectly altering glutamate receptor activity and releasing BDNF, thereby affecting neuroplasticity.

At the same time, studies have shown that Tianeptine may have possible anticonvulsant (anti-seizure) and analgesic (pain-relieving) activities through direct or downstream modulation of adenosine A1 receptors.

Application

Mainly used in antidepressant, antiepileptic products.

Mainly used in antidepressant, antiepileptic products

Pharmacology 

Tianeptine Sodium Powder is an antidepressant, the animal pharmacological research results show that:  

1. Increase the spontaneous activity of pyramidal cells in the hippocampus and accelerate the recovery of their function after inhibition.

2. Increase the reabsorption of serotonin by neurons in the cerebral cortex and hippocampus.

pharmacology

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Extraction-process

Extraction process flow chart

Certificate

product certificate

Package

product package

transportion

In today's fierce competition in the market, the company always believes that the public demand, product quality, fast service is the fundamental condition for the survival of enterprises, and humanized products and services have always made us stand in the forefront of the Tianeptine Free Acid and Tianeptine Sodium Powder CAS 30123-17-2 industry. We insist on giving top priority to the health and safety of our employees, treating every employee with respect and equality, and safeguarding and protecting all the legal rights and interests of our employees. Our company upholds the spirit of 'innovation, harmony, team work and sharing, trails, pragmatic progress'.

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