Xi'an Prius Biological Engineering Co.,Ltd
Address:Room 0836, Euro-Asia International Building A, Ouya avenue, Xi'an, Shaanxi Province, China
Zip code:710038
Phone:+86-17792290970
Mail:sales@prsbiotech.com
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Saponins are the foundation of the health-preserving and curing effects of Panax notoginseng and the main active ingredient. So far, more than 70 monomeric saponins have been isolated from different parts of it, some of which are unique to Panax notoginseng, and the most are Rg1, Rb1, R1, and Rd. The content of notoginseng saponins is one of the main criteria for evaluating the intrinsic quality of notoginseng.
The efficacy of the main monomer saponins of Panax notoginseng:
Ginsenoside Rb2
Inhibit central nervous system, promote DNA and RNA synthesis, anti-hemolysis, anti-diabetic;
Ginsenoside Rd
Enhance immune function and inhibit the growth of cancer cells;
Ginsenoside Rh2
Promote the transformation of cancer cells into non-cancer cells;
Ginsenoside Rg1
Stimulate the central nervous system, enhance memory, resist fatigue, promote DNA and RNA synthesis, and resist platelet aggregation;
Ginsenoside Rg2
Anti-platelet aggregation;
Ginsenoside Rh1
Promote the transformation of cancer cells into non-cancer cells;
Ginsenoside Rb2
Induce the differentiation of leukemia cells.
Pharmacological effects of panax notoginseng saponins:
Effect on hyperlipidemia
It has obvious anti-platelet aggregation and defibrinating effects, and it has obvious preventive and therapeutic effects on hyperlipidemia.
Effect on hyperviscosity
It can significantly reduce the surface activity of platelets, inhibit platelet adhesion and aggregation, resist thrombosis, and improve microcirculation.
Effect on hypertension
Using panax notoginseng saponins to treat hypertension, after 20 days of treatment, can significantly reduce blood pressure, significantly slow down heart rate, increase red blood cell deformability, and reduce red blood cell aggregation.
Anti-myocardial ischemia effect
It can significantly improve the performance of ischemia and reduce the scope of myocardial infarction. It can reverse the left ventricular diastolic dysfunction of patients with fatigue-type angina and even restore it to normal.
Anti-arrhythmia
It can significantly shorten the duration of arrhythmia and reduce the incidence of acute myocardial infarction and arrhythmia.
Anti-atherosclerosis effect
It has a protective effect on vascular smooth muscle cells, can protect cells from high-fat serum, and has a certain preventive effect on atherosclerosis.
Anti-thrombosis, improve microcirculation
It can significantly reduce the surface activity of platelets, inhibit platelet aggregation and adhesion, resist thrombosis, and improve microcirculation.
Anti-cardiocerebral ischemia effect
It has a good clinical treatment effect on the acute phase of cerebral infarction, and it can significantly improve cerebral edema during global cerebral ischemia or focal ischemia-reperfusion.
Promote the growth of hematopoietic cells
Studies have found that Rg1 and Rb1 in Panax notoginseng saponins are effective monomers for promoting hematopoiesis, which can continuously promote the proliferation of human bone marrow granule and erythroid hematopoietic progenitor cells.
Protective effect on nerve cell damage
Panax notoginseng saponins have a protective effect on nerve cell damage caused by energy metabolism disorders.
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