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"From the molecular level, we believe that EGCG can be wrapped in the surface of toxic oligomers, and thus change its growth and the way of interaction with healthy cells." The author of the article, from the Department of Chemistry and Chemical Biology professor Dr. Dr. said.
This result is based on a decade of NMR technology, and the results are published in the Journal of the American Chemical Society in the form of a cover article. This result may be able to lead the development of new drug development and treatment methods.
Despite the decades of hard work in this area, the mechanism of Alzheimer's disease is still not fully revealed, and the means of treatment is also very limited. "We all know that there is no effective therapy for Alzheimer's disease, so the best way to deal with is to actively prevent this means that the use of green tea extract can be 15 to 25 years ago to play an effective preventive effect."
Next, the researchers plan to modify the EGCG to make it a regular food additive. For example, the current EGCG at room temperature is not stable, and therefore difficult to be directly absorbed by the body.