Minoxidil 100% was the first drug approved by the FDA for the treatment of androgenetic alopecia (hair loss). Before that, Minoxidil sulphate had been used as vasodilator drug prescribed as oral tablet to treat high blood pressure, with side effects that included hair growth and reversal of male baldness. In the 1980s, UpJohn Corporation came out with a topical solution of 2% minoxidil, called Rogaine, for the specific treatment of androgenetic alopecia. Since the 1990s, numerous generic forms of Minoxidil 100% have become available to treat hair loss while the oral form is still used to treat high blood pressure.
Function of Minoxidil 100%：
It is used for refractory hypertension and renal hypertension, the antihypertensive effects of hydralazine stronger than that. Mechanism for the K + channel opening, so that vascular smooth muscle. it Is a vasodilator antihypertensive drug classes. Does not cause orthostatic hypotension, no long-term efficacy of medication .
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