Febrifugine is a quinazolinone alkaloid first isolated from the Chinese herb Dichroa febrifuga, but also found in the garden plant Hydrangea. Laboratory synthesis of febrifugine determined that the originally reported stereochemistry was incorrect.
Febrifugine is a quinazolinone alkaloid first isolated from the Chinese herb Dichroa febrifuga, but also found in the garden plant Hydrangea.Laboratory synthesis of febrifugine determined that the originally reported stereochemistry was incorrect.
Febrifugine has antimalarial properties and the synthetic halogenated derivative halofuginone is used in veterinary medicine as a coccidiostat. Other synthetic febrifugine derivatives have been used against malaria, cancer, fibrosis, and inflammatory disease.
Febrifugine/Dichroa Febrifuga powder
C 63.77%; H 6.35%; N 13.94%; O 15.93%
Shows high degree of antimalarial activity,antipyretic and emetic activities
Mp 139-140℃. Mp 154-156℃(dimorph.)
[α]25D +6 (c, 0.5 in CHCl3) (c, 0.5 in EtOH)
Partition Coefficient (Calculated):
Log P-0.33 (calc)
Used for content determination of/identification/pharmacology experiment, etc
2-8°C refrigerated, sealed, avoid light
The period of validity:
COA of Febrifugine:
A.H-NMR:Comply with the structure
B.LC-MS:Comply with the structure
C.The IR spectrum of sample should be identical with that of reference standard;
The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.
meets the requirements.
Loss on drying
≤0.5%, determined on 1.0 g.
Unspecified impurities: for each impurity
99.0%~101.0% (anhydrous substance).
Total plate count
Yeast and Moulds
Preserve in well-closed, light-resistant and airtight containers.
Storage: Store in cool & dry place, Keep away from strong light and heat.
Shelf life: 24Months when properly stored.
Packing: 10g/one bag
Or according to customers' request.
1.By courier ,Like DHL ,UPS, FEDEX etc. Door to door and fast. 3-5days
2.By air to the air port.
3.By sea to sea port ,usually 10-30days,but is is economy.
Q1.Can I get some samples? A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2: How to start orders or make payments? A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union or Paypal or Escrow(Alibaba).
Q3: How to confirm the Product Quality before placing orders? A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q4:What’s your MOQ? A:Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
Q5: How about delivery leadtime? A:About 3-5 days after payment confirmed. (Chinese holiday not included)
Q6:Is there a discount? A:Different quantity has different discount.