Dichroa Febrifuga Powder

Dichroa Febrifuga Powder

Dichroa Febrifuga Powder is extracted from the dried roots of Dichroa Febrifuga. It contains a variety of alkaloids, such as α-, β-, γ-dichroine, dichroidine, 4-quinazolone), dicnrin A, umbeli-ferone), and dictirin B. α-, β-, γ-dichroine have special effects on malaria.

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Product Details

Dichroa Febrifuga Powder

Dichroa Febrifuga Powder is extracted from the dried roots of Dichroa Febrifuga. It contains a variety of alkaloids, such as α-, β-, γ-dichroine, dichroidine, 4-quinazolone), dicnrin A, umbeli-ferone), and dictirin B. α-, β-, γ-dichroine have special effects on malaria. γ-dichroine has the strongest anti-malarial effect, and its effect is about 98-152 times that of quinine hydrochloride. β-dichroine is 89-122 times that of quinine, and the total alkali is about 26 times that of quinine.


1. Has an inhibitory effect on influenza A virus (PR8).

2. Alkaloids have a strong inhibitory effect on malaria parasites.

3. Has antihypertensive effect

4. Can stimulate the gastrointestinal tract and act on the vomiting center, causing vomiting.

detailed description plant extract.jpg

Product:Febrifugine
CAS:24159-07-7
Molecular formula:C16H19N3O3
Molecular weight:301.344
Accurate Mass:301.142642
Percentage Composition:C 63.77%; H 6.35%; N 13.94%; O 15.93%
Physical Description:White crystal
Biological Source:Dichroa febrifuga
Biological Use/Importance:Shows high degree of antimalarial activity,antipyretic and emetic activities
Melting Point:Mp 139-140℃. Mp 154-156℃(dimorph.)
Optical Rotation:[α]25D +6 (c, 0.5 in CHCl3) (c, 0.5 in EtOH)

Partition Coefficient (Calculated):Log P-0.33 (calc)
Assay:≥ 98%
USES:Used for content determination of/identification/pharmacology experiment, etc

Febrifugine Pure Natural Plant Extract Herbal Powders Dichroa Febrifuga Extract Feerifuqine Powder.jpg

COA of Febrifugine:

ItemStandardTest Results

Identification

A.H-NMR:Comply with the structure

Complies

B.LC-MS:Comply with the structure

Complies

C.The IR spectrum of sample should be identical with that of reference standard;

Complies

D.HPLC-ESI-MS

The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.

Complies

Crystallinity

meets the requirements.

Complies

Loss on drying

≤2.0%

0.19%

Heavy metals

≤10 ppm

<10ppm

Water

≤1.0%

0.1%

Sulphated ash

≤0.5%, determined on 1.0 g.

0.009%

Related substances

Unspecified impurities: for each impurity

≤0.10%

<0.10%

Total Impurity

≤0.5%

0.18%

Purity

≥99.0%

99.7%

Assay

99.0%~101.0% (anhydrous substance).

99.8%


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